KRTAP4-9 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KRTAP4-9 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KRTAP4-9 at tissue level.

III. Associated gene sets

GO_0042633Biological processhair cycle
GO_0005829Cellular componentcytosol
GO_0045095Cellular componentkeratin filament

IV. Literature review

[source]
Gene nameKRTAP4-9
Protein nameKeratin-associated protein 4-9 (Keratin-associated protein 4.9) (Ultrahigh sulfur keratin-associated protein 4.9)
HCG2043351 (Keratin-associated protein 4-9)
SynonymsKRTAP4.9
hCG_2043351
KAP4.9
DescriptionFUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

FUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. .

AccessionsENST00000574465.1
ENST00000391415.2
Q9BYQ8
ENST00000709616.1
A0A0G2JLF9