KRTAP4-8 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KRTAP4-8 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KRTAP4-8 at tissue level.

III. Associated gene sets

GO_0042633Biological processhair cycle
GO_0005829Cellular componentcytosol
GO_0045095Cellular componentkeratin filament

IV. Literature review

[source]
Gene nameKRTAP4-8
Protein nameHCG2042992 (Keratin-associated protein 4-8)
Keratin-associated protein 4-8 (Keratin-associated protein 4.8) (Ultrahigh sulfur keratin-associated protein 4.8)
Keratin-associated protein 4-8
SynonymsKRTAP4.8
hCG_2042992
KAP4.8
DescriptionFUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

FUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. .

FUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. .

AccessionsA0A0G2JPP1
ENST00000709606.1
ENST00000333822.5
A0A0G2JLE6
ENST00000612944.1
Q9BYQ9
ENST00000574631.2