I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| club cell | 6 studies | 26% ± 8% | |
| squamous epithelial cell | 4 studies | 50% ± 19% | |
| type I pneumocyte | 3 studies | 23% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| club cell | 6 studies | 26% ± 8% | |
| squamous epithelial cell | 4 studies | 50% ± 19% | |
| type I pneumocyte | 3 studies | 23% ± 9% |
Insufficient scRNA-seq data for expression of KLK10 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 96% | 862.86 | 172 / 180 | 93% | 115.74 | 399 / 430 |
| esophagus | 42% | 6114.01 | 609 / 1445 | 80% | 90.47 | 146 / 183 |
| lung | 73% | 369.25 | 421 / 578 | 37% | 19.09 | 433 / 1155 |
| skin | 73% | 1901.38 | 1323 / 1809 | 8% | 4.47 | 39 / 472 |
| prostate | 67% | 310.20 | 165 / 245 | 12% | 1.67 | 62 / 502 |
| uterus | 28% | 290.01 | 47 / 170 | 47% | 39.58 | 218 / 459 |
| pancreas | 0% | 2.36 | 1 / 328 | 72% | 48.00 | 129 / 178 |
| intestine | 8% | 27.12 | 77 / 966 | 59% | 33.04 | 309 / 527 |
| breast | 47% | 329.78 | 217 / 459 | 17% | 6.96 | 186 / 1118 |
| thymus | 1% | 4.07 | 9 / 653 | 61% | 38.43 | 372 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 51% | 34.54 | 23 / 45 |
| stomach | 5% | 19.72 | 17 / 359 | 41% | 19.45 | 118 / 286 |
| bladder | 0% | 0 | 0 / 21 | 27% | 14.56 | 136 / 504 |
| adipose | 25% | 165.37 | 306 / 1204 | 0% | 0 | 0 / 0 |
| brain | 12% | 31.49 | 306 / 2642 | 0% | 0 | 0 / 705 |
| adrenal gland | 0% | 2.44 | 1 / 258 | 3% | 0.83 | 7 / 230 |
| liver | 0% | 0 | 0 / 226 | 2% | 0.69 | 10 / 406 |
| heart | 2% | 4.06 | 13 / 861 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 1% | 0.10 | 6 / 901 |
| blood vessel | 0% | 1.98 | 5 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 0% | 1.83 | 3 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 4.22 | 2 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006508 | Biological process | proteolysis |
| GO_0030141 | Cellular component | secretory granule |
| GO_0005576 | Cellular component | extracellular region |
| GO_0008236 | Molecular function | serine-type peptidase activity |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| Gene name | KLK10 |
| Protein name | Kallikrein related peptidase 10 KLK10 protein (Kallikrein 10 splice variant 3) (Kallikrein J) (cDNA FLJ76060, highly similar to Homo sapiens kallikrein 10 (KLK10), transcript variant 1, mRNA) Kallikrein 10 protein 2 Kallikrein-related peptidase 10 transcript variant 5 Kallikrein 10 protein 5 Kallikrein 10 protein 4 Kallikrein 10 protein 12 Kallikrein 10 protein 8 Kallikrein-10 (EC 3.4.21.-) (Normal epithelial cell-specific 1) (Protease serine-like 1) Kallikrein 10 protein 9 Kallikrein 10 protein 13 Kallikrein 10 protein 1 Kallikrein 10 protein 3 (Kallikrein 10 protein 7) |
| Synonyms | NES1 PRSSL1 KLNJ |
| Description | FUNCTION: Has a tumor-suppressor role for NES1 in breast and prostate cancer. |
| Accessions | W8GJG8 W8GWD1 W8GN28 W8GIU9 ENST00000391805.5 W8GJG4 W8GWD5 O43240 M0R2S4 Q6ICR6 ENST00000309958.7 A0A1W5R407 W8GRM7 ENST00000358789.8 W8GIV4 W8GN33 ENST00000599077.1 ENST00000601467.1 M0R132 |
