Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| pericyte | 6 studies | 27% ± 8% | |
| endothelial cell | 4 studies | 23% ± 6% | |
| myofibroblast cell | 3 studies | 19% ± 4% | |
| smooth muscle cell | 3 studies | 22% ± 5% | |
| neuron | 3 studies | 39% ± 12% | |
| fibroblast | 3 studies | 18% ± 3% |
Insufficient scRNA-seq data for expression of KLHDC8B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 13951.12 | 258 / 258 | 100% | 208.61 | 230 / 230 |
| thymus | 100% | 3381.14 | 653 / 653 | 100% | 81.74 | 605 / 605 |
| ovary | 100% | 8135.91 | 180 / 180 | 100% | 37.13 | 428 / 430 |
| skin | 99% | 2327.12 | 1796 / 1809 | 100% | 87.19 | 472 / 472 |
| prostate | 100% | 2092.07 | 245 / 245 | 99% | 41.76 | 498 / 502 |
| uterus | 100% | 2966.49 | 170 / 170 | 99% | 55.13 | 455 / 459 |
| breast | 100% | 2982.32 | 459 / 459 | 99% | 42.40 | 1104 / 1118 |
| kidney | 100% | 1646.39 | 89 / 89 | 98% | 36.64 | 883 / 901 |
| lung | 100% | 2104.64 | 577 / 578 | 94% | 39.44 | 1090 / 1155 |
| brain | 93% | 1076.56 | 2454 / 2642 | 100% | 45.25 | 705 / 705 |
| bladder | 100% | 3330.62 | 21 / 21 | 92% | 40.18 | 462 / 504 |
| liver | 83% | 711.73 | 188 / 226 | 93% | 27.11 | 377 / 406 |
| esophagus | 100% | 4167.14 | 1445 / 1445 | 69% | 14.37 | 126 / 183 |
| pancreas | 68% | 530.59 | 224 / 328 | 96% | 35.59 | 171 / 178 |
| stomach | 96% | 1654.23 | 343 / 359 | 65% | 12.31 | 187 / 286 |
| intestine | 95% | 3973.09 | 921 / 966 | 62% | 11.59 | 325 / 527 |
| eye | 0% | 0 | 0 / 0 | 100% | 111.49 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 48.44 | 29 / 29 |
| spleen | 100% | 1651.10 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 43.45 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 37.41 | 1 / 1 |
| adipose | 100% | 3036.79 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| heart | 100% | 3895.30 | 860 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 1864.65 | 1326 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 98% | 1808.58 | 788 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 48% | 541.03 | 448 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1902410 | Biological process | mitotic cytokinetic process |
| GO_0098813 | Biological process | nuclear chromosome segregation |
| GO_0140014 | Biological process | mitotic nuclear division |
| GO_0030496 | Cellular component | midbody |
| GO_0005829 | Cellular component | cytosol |
| GO_0110070 | Cellular component | cellularization cleavage furrow |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0045171 | Cellular component | intercellular bridge |
| Gene name | KLHDC8B |
| Protein name | Kelch domain-containing protein 8B |
| Synonyms | FP17659 |
| Description | FUNCTION: Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis . Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells . . |
| Accessions | ENST00000332780.4 Q96DZ8 Q8IXV7 |
