KIF25 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of KIF25 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	99%	243.49	2622 / 2642	7%	0.15	46 / 705
breast	90%	112.05	413 / 459	7%	0.15	77 / 1118
lung	80%	37.83	463 / 578	12%	0.27	144 / 1155
adipose	91%	146.19	1101 / 1204	0%	0	0 / 0
ovary	73%	42.04	131 / 180	6%	0.11	25 / 430
prostate	69%	33.57	170 / 245	8%	0.16	40 / 502
eye	0%	0	0 / 0	73%	2.31	58 / 80
bladder	67%	20.81	14 / 21	5%	0.15	23 / 504
muscle	67%	23.32	538 / 803	0%	0	0 / 0
liver	58%	21.72	131 / 226	8%	0.19	32 / 406
skin	43%	10.54	781 / 1809	18%	0.55	84 / 472
heart	61%	21.64	522 / 861	0%	0	0 / 0
uterus	51%	18.68	87 / 170	8%	0.21	36 / 459
intestine	49%	16.46	474 / 966	9%	0.17	50 / 527
spleen	58%	16.76	140 / 241	0%	0	0 / 0
kidney	55%	18.04	49 / 89	2%	0.04	17 / 901
thymus	48%	14.89	312 / 653	8%	0.32	47 / 605
stomach	26%	6.36	94 / 359	5%	0.09	15 / 286
esophagus	26%	6.48	377 / 1445	5%	0.20	9 / 183
lymph node	0%	0	0 / 0	21%	0.29	6 / 29
blood vessel	14%	4.23	182 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	13%	0.42	6 / 45
adrenal gland	8%	4.04	20 / 258	1%	0.02	2 / 230
pancreas	7%	1.43	22 / 328	1%	0.01	1 / 178
peripheral blood	0%	0.13	4 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0010507	Biological process	negative regulation of autophagy
GO_0051294	Biological process	establishment of spindle orientation
GO_0051647	Biological process	nucleus localization
GO_0007018	Biological process	microtubule-based movement
GO_0046603	Biological process	negative regulation of mitotic centrosome separation
GO_0006996	Biological process	organelle organization
GO_0000070	Biological process	mitotic sister chromatid segregation
GO_0051289	Biological process	protein homotetramerization
GO_0005874	Cellular component	microtubule
GO_0005813	Cellular component	centrosome
GO_0005871	Cellular component	kinesin complex
GO_0005737	Cellular component	cytoplasm
GO_0008569	Molecular function	minus-end-directed microtubule motor activity
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0003777	Molecular function	microtubule motor activity
GO_0008017	Molecular function	microtubule binding
GO_0005524	Molecular function	ATP binding

Gene name	KIF25
Protein name	Kinesin-like protein KIF25 (Kinesin-like protein 3) Kinesin family member 25
Synonyms	KNSL3
Description	FUNCTION: Minus-end microtubule-dependent motor protein (By similarity). Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase . Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis . May also act as a negative regulator of amino acid starvation-induced autophagy . .
Accessions	ENST00000643607.3 [Q9UIL4-1] A0A494C0P5 ENST00000443060.6 [Q9UIL4-1] ENST00000652547.1 Q9UIL4

KIF25 report