I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 5 studies | 37% ± 15% | |
| GABAergic neuron | 4 studies | 29% ± 11% | |
| interneuron | 3 studies | 32% ± 12% | |
| neuron | 3 studies | 23% ± 4% | |
| astrocyte | 3 studies | 21% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 5 studies | 37% ± 15% | |
| GABAergic neuron | 4 studies | 29% ± 11% | |
| interneuron | 3 studies | 32% ± 12% | |
| neuron | 3 studies | 23% ± 4% | |
| astrocyte | 3 studies | 21% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 29% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 98% | 4472.50 | 2592 / 2642 | 98% | 38.96 | 693 / 705 |
| lung | 99% | 2199.00 | 572 / 578 | 66% | 3.49 | 764 / 1155 |
| intestine | 48% | 1118.02 | 464 / 966 | 94% | 8.66 | 498 / 527 |
| stomach | 39% | 373.57 | 139 / 359 | 93% | 8.81 | 266 / 286 |
| breast | 56% | 505.76 | 259 / 459 | 52% | 2.37 | 579 / 1118 |
| bladder | 43% | 394.95 | 9 / 21 | 61% | 3.81 | 306 / 504 |
| spleen | 100% | 5805.43 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 100% | 7032.53 | 927 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 13.83 | 28 / 29 |
| esophagus | 13% | 107.51 | 194 / 1445 | 74% | 5.09 | 136 / 183 |
| pancreas | 4% | 29.18 | 12 / 328 | 83% | 4.33 | 147 / 178 |
| uterus | 13% | 89.71 | 22 / 170 | 53% | 2.39 | 245 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 64% | 3.15 | 29 / 45 |
| liver | 18% | 163.20 | 41 / 226 | 44% | 2.37 | 178 / 406 |
| kidney | 24% | 267.53 | 21 / 89 | 38% | 1.47 | 345 / 901 |
| adipose | 62% | 594.66 | 744 / 1204 | 0% | 0 | 0 / 0 |
| skin | 6% | 42.86 | 101 / 1809 | 54% | 3.72 | 256 / 472 |
| thymus | 23% | 311.74 | 153 / 653 | 23% | 1.84 | 140 / 605 |
| prostate | 21% | 178.69 | 51 / 245 | 11% | 0.39 | 56 / 502 |
| ovary | 5% | 33.72 | 9 / 180 | 23% | 0.77 | 99 / 430 |
| adrenal gland | 6% | 47.50 | 16 / 258 | 13% | 0.53 | 31 / 230 |
| blood vessel | 15% | 151.68 | 198 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 10% | 0.82 | 8 / 80 |
| heart | 2% | 17.25 | 19 / 861 | 0% | 0 | 0 / 0 |
| muscle | 0% | 1.97 | 2 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007018 | Biological process | microtubule-based movement |
| GO_0005871 | Cellular component | kinesin complex |
| GO_0030426 | Cellular component | growth cone |
| GO_0005874 | Cellular component | microtubule |
| GO_0031410 | Cellular component | cytoplasmic vesicle |
| GO_0030425 | Cellular component | dendrite |
| GO_0003777 | Molecular function | microtubule motor activity |
| GO_0008017 | Molecular function | microtubule binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | KIF21B |
| Protein name | Kinesin-like protein KIF21B variant Kinesin-like protein KIF21B |
| Synonyms | KIAA0449 |
| Description | FUNCTION: Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface. . |
| Accessions | ENST00000332129.6 [O75037-2] ENST00000461742.7 [O75037-4] ENST00000360529.9 [O75037-3] ENST00000422435.2 [O75037-1] O75037 Q2UVF0 |
