KCNV1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KCNV1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KCNV1 at tissue level.

III. Associated gene sets

GO_0051260Biological processprotein homooligomerization
GO_0006813Biological processpotassium ion transport
GO_0001508Biological processaction potential
GO_0071805Biological processpotassium ion transmembrane transport
GO_0005886Cellular componentplasma membrane
GO_0008076Cellular componentvoltage-gated potassium channel complex
GO_0016020Cellular componentmembrane
GO_0045171Cellular componentintercellular bridge
GO_0015459Molecular functionpotassium channel regulator activity
GO_0005249Molecular functionvoltage-gated potassium channel activity
GO_0008200Molecular functionion channel inhibitor activity

IV. Literature review

[source]
Gene nameKCNV1
Protein namePotassium voltage-gated channel subfamily V member 1 (Neuronal potassium channel alpha subunit HNKA) (Voltage-gated potassium channel subunit Kv8.1)
Potassium voltage-gated channel subfamily V member 1 (Voltage-gated potassium channel subunit Kv8.1)
Synonyms
DescriptionFUNCTION: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes. .

FUNCTION: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes. .

AccessionsQ6PIU1
Q76FP2
ENST00000524391.6
ENST00000297404.1