KCNJ1 | OmnibusX

Name	Number of supported studies	Average coverage
kidney loop of Henle epithelial cell	7 studies	41% ± 13%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	56% ± 22%	Explore
kidney connecting tubule epithelial cell	3 studies	66% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of KCNJ1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	7715.53	89 / 89	25%	10.28	225 / 901
lung	95%	42.44	551 / 578	7%	0.33	77 / 1155
thymus	83%	45.12	545 / 653	16%	1.00	97 / 605
spleen	97%	32.41	233 / 241	0%	0	0 / 0
adipose	90%	37.02	1082 / 1204	0%	0	0 / 0
brain	85%	104.73	2250 / 2642	2%	0.03	14 / 705
breast	82%	27.17	377 / 459	1%	0.03	12 / 1118
skin	71%	54.31	1288 / 1809	0%	0	0 / 472
prostate	69%	12.37	168 / 245	0%	0.01	2 / 502
intestine	65%	11.58	626 / 966	0%	0	0 / 527
heart	64%	10.96	551 / 861	0%	0	0 / 0
adrenal gland	63%	14.58	163 / 258	0%	0.01	1 / 230
esophagus	61%	10.19	881 / 1445	0%	0	0 / 183
bladder	57%	8.86	12 / 21	2%	0.06	9 / 504
pancreas	59%	9.27	192 / 328	0%	0	0 / 178
uterus	54%	8.36	92 / 170	3%	0.11	12 / 459
blood vessel	51%	9.83	679 / 1335	0%	0	0 / 0
stomach	47%	6.90	168 / 359	0%	0.00	1 / 286
peripheral blood	29%	4.76	269 / 929	0%	0	0 / 0
ovary	27%	4.53	48 / 180	2%	0.04	8 / 430
muscle	20%	2.29	162 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	17%	1.62	5 / 29
liver	15%	1.58	33 / 226	0%	0	0 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0034765	Biological process	regulation of monoatomic ion transmembrane transport
GO_1990573	Biological process	potassium ion import across plasma membrane
GO_0034702	Cellular component	monoatomic ion channel complex
GO_0005886	Cellular component	plasma membrane
GO_0005546	Molecular function	phosphatidylinositol-4,5-bisphosphate binding
GO_0015272	Molecular function	ATP-activated inward rectifier potassium channel activity
GO_0005242	Molecular function	inward rectifier potassium channel activity
GO_0005524	Molecular function	ATP binding

Gene name	KCNJ1
Protein name	ATP-sensitive inward rectifier potassium channel 1 (ATP-regulated potassium channel ROM-K) (Inward rectifier K(+) channel Kir1.1) (Potassium channel, inwardly rectifying subfamily J member 1)
Synonyms	ROMK1
Description	FUNCTION: In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium. .
Accessions	ENST00000392666.6 [P48048-2] ENST00000392665.6 [P48048-2] ENST00000440599.6 [P48048-2] ENST00000324036.7 [P48048-2] P48048 ENST00000392664.2 [P48048-1]

KCNJ1 report