KCNJ1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KCNJ1 at tissue level.

III. Associated gene sets

GO_0034765Biological processregulation of monoatomic ion transmembrane transport
GO_1990573Biological processpotassium ion import across plasma membrane
GO_0034702Cellular componentmonoatomic ion channel complex
GO_0005886Cellular componentplasma membrane
GO_0005546Molecular functionphosphatidylinositol-4,5-bisphosphate binding
GO_0015272Molecular functionATP-activated inward rectifier potassium channel activity
GO_0005242Molecular functioninward rectifier potassium channel activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameKCNJ1
Protein nameATP-sensitive inward rectifier potassium channel 1 (ATP-regulated potassium channel ROM-K) (Inward rectifier K(+) channel Kir1.1) (Potassium channel, inwardly rectifying subfamily J member 1)
SynonymsROMK1
DescriptionFUNCTION: In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium. .

AccessionsENST00000392666.6 [P48048-2]
ENST00000392665.6 [P48048-2]
ENST00000440599.6 [P48048-2]
ENST00000324036.7 [P48048-2]
P48048
ENST00000392664.2 [P48048-1]