Name | Number of supported studies | Average coverage | |
---|---|---|---|
kidney loop of Henle epithelial cell | 7 studies | 41% ± 13% | |
kidney distal convoluted tubule epithelial cell | 4 studies | 56% ± 22% | |
kidney connecting tubule epithelial cell | 3 studies | 66% ± 5% |
Insufficient scRNA-seq data for expression of KCNJ1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 7715.53 | 89 / 89 | 25% | 10.28 | 225 / 901 |
lung | 95% | 42.44 | 551 / 578 | 7% | 0.33 | 77 / 1155 |
thymus | 83% | 45.12 | 545 / 653 | 16% | 1.00 | 97 / 605 |
spleen | 97% | 32.41 | 233 / 241 | 0% | 0 | 0 / 0 |
adipose | 90% | 37.02 | 1082 / 1204 | 0% | 0 | 0 / 0 |
brain | 85% | 104.73 | 2250 / 2642 | 2% | 0.03 | 14 / 705 |
breast | 82% | 27.17 | 377 / 459 | 1% | 0.03 | 12 / 1118 |
skin | 71% | 54.31 | 1288 / 1809 | 0% | 0 | 0 / 472 |
prostate | 69% | 12.37 | 168 / 245 | 0% | 0.01 | 2 / 502 |
intestine | 65% | 11.58 | 626 / 966 | 0% | 0 | 0 / 527 |
heart | 64% | 10.96 | 551 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 63% | 14.58 | 163 / 258 | 0% | 0.01 | 1 / 230 |
esophagus | 61% | 10.19 | 881 / 1445 | 0% | 0 | 0 / 183 |
bladder | 57% | 8.86 | 12 / 21 | 2% | 0.06 | 9 / 504 |
pancreas | 59% | 9.27 | 192 / 328 | 0% | 0 | 0 / 178 |
uterus | 54% | 8.36 | 92 / 170 | 3% | 0.11 | 12 / 459 |
blood vessel | 51% | 9.83 | 679 / 1335 | 0% | 0 | 0 / 0 |
stomach | 47% | 6.90 | 168 / 359 | 0% | 0.00 | 1 / 286 |
peripheral blood | 29% | 4.76 | 269 / 929 | 0% | 0 | 0 / 0 |
ovary | 27% | 4.53 | 48 / 180 | 2% | 0.04 | 8 / 430 |
muscle | 20% | 2.29 | 162 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 17% | 1.62 | 5 / 29 |
liver | 15% | 1.58 | 33 / 226 | 0% | 0 | 0 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0034765 | Biological process | regulation of monoatomic ion transmembrane transport |
GO_1990573 | Biological process | potassium ion import across plasma membrane |
GO_0034702 | Cellular component | monoatomic ion channel complex |
GO_0005886 | Cellular component | plasma membrane |
GO_0005546 | Molecular function | phosphatidylinositol-4,5-bisphosphate binding |
GO_0015272 | Molecular function | ATP-activated inward rectifier potassium channel activity |
GO_0005242 | Molecular function | inward rectifier potassium channel activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | KCNJ1 |
Protein name | ATP-sensitive inward rectifier potassium channel 1 (ATP-regulated potassium channel ROM-K) (Inward rectifier K(+) channel Kir1.1) (Potassium channel, inwardly rectifying subfamily J member 1) |
Synonyms | ROMK1 |
Description | FUNCTION: In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium. . |
Accessions | ENST00000392666.6 [P48048-2] ENST00000392665.6 [P48048-2] ENST00000440599.6 [P48048-2] ENST00000324036.7 [P48048-2] P48048 ENST00000392664.2 [P48048-1] |