Insufficient scRNA-seq data for expression of KCNH6 at single-cell level.
Insufficient scRNA-seq data for expression of KCNH6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 92% | 795.12 | 225 / 245 | 93% | 17.93 | 465 / 502 |
| kidney | 96% | 997.67 | 85 / 89 | 52% | 2.40 | 467 / 901 |
| pancreas | 97% | 124.84 | 317 / 328 | 41% | 6.55 | 73 / 178 |
| brain | 80% | 93.42 | 2112 / 2642 | 8% | 0.14 | 54 / 705 |
| stomach | 73% | 68.42 | 263 / 359 | 11% | 1.07 | 32 / 286 |
| lung | 68% | 59.62 | 392 / 578 | 5% | 0.67 | 61 / 1155 |
| adrenal gland | 12% | 4.97 | 31 / 258 | 53% | 2.25 | 121 / 230 |
| intestine | 46% | 160.55 | 443 / 966 | 12% | 0.75 | 64 / 527 |
| esophagus | 1% | 0.63 | 20 / 1445 | 9% | 1.01 | 17 / 183 |
| liver | 0% | 0.10 | 1 / 226 | 10% | 4.56 | 39 / 406 |
| bladder | 5% | 1.19 | 1 / 21 | 4% | 3.39 | 22 / 504 |
| breast | 1% | 1.60 | 5 / 459 | 7% | 0.45 | 76 / 1118 |
| uterus | 2% | 1.14 | 3 / 170 | 4% | 0.10 | 18 / 459 |
| thymus | 5% | 1.36 | 32 / 653 | 0% | 0.01 | 2 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 4% | 4.68 | 2 / 45 |
| ovary | 1% | 0.35 | 2 / 180 | 3% | 0.10 | 11 / 430 |
| skin | 3% | 0.95 | 48 / 1809 | 0% | 0 | 0 / 472 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.21 | 2 / 80 |
| adipose | 1% | 0.43 | 15 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.06 | 2 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.19 | 2 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0060307 | Biological process | regulation of ventricular cardiac muscle cell membrane repolarization |
| GO_0086013 | Biological process | membrane repolarization during cardiac muscle cell action potential |
| GO_0086091 | Biological process | regulation of heart rate by cardiac conduction |
| GO_0071805 | Biological process | potassium ion transmembrane transport |
| GO_0034702 | Cellular component | monoatomic ion channel complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005242 | Molecular function | inward rectifier potassium channel activity |
| Gene name | KCNH6 |
| Protein name | Potassium voltage-gated channel subfamily H member 6 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (hERG-2) (hERG2) (Voltage-gated potassium channel subunit Kv11.2) |
| Synonyms | ERG2 |
| Description | FUNCTION: Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current (By similarity). Channel properties may be modulated by cAMP and subunit assembly. . |
| Accessions | Q9H252 J9JID4 J3KSC2 ENST00000456941.6 [Q9H252-2] ENST00000583465.1 ENST00000583023.1 [Q9H252-1] ENST00000314672.10 ENST00000581784.5 [Q9H252-2] ENST00000580652.5 [Q9H252-3] |