IGSF5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of IGSF5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of IGSF5 at tissue level.

III. Associated gene sets

GO_0098609Biological processcell-cell adhesion
GO_0016324Cellular componentapical plasma membrane
GO_0009986Cellular componentcell surface
GO_0005923Cellular componentbicellular tight junction

IV. Literature review

[source]
Gene nameIGSF5
Protein nameAlternative protein IGSF5
Immunoglobulin superfamily member 5 (IgSF5) (Junctional adhesion molecule 4) (JAM-4)
SynonymsJAM4
DescriptionFUNCTION: Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity). .

AccessionsQ9NSI5
L8E8K9
ENST00000380588.5