IDO2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of IDO2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of IDO2 at tissue level.

III. Associated gene sets

GO_0019441Biological processtryptophan catabolic process to kynurenine
GO_0002376Biological processimmune system process
GO_0034354Biological process'de novo' NAD biosynthetic process from tryptophan
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0020037Molecular functionheme binding
GO_0033754Molecular functionindoleamine 2,3-dioxygenase activity
GO_0046872Molecular functionmetal ion binding
GO_0004833Molecular functiontryptophan 2,3-dioxygenase activity

IV. Literature review

[source]
Gene nameIDO2
Protein nameIndoleamine 2,3-dioxygenase 2 (IDO-2) (EC 1.13.11.-) (Indoleamine 2,3-dioxygenase-like protein 1) (Indoleamine-pyrrole 2,3-dioxygenase-like protein 1)
Alternative protein IDO2
SynonymsINDOL1
DescriptionFUNCTION: Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway . Involved in immune regulation. May not play a significant role in tryptophan-related tumoral resistance . .

AccessionsENST00000502986.4 [Q6ZQW0-1]
L8E9C5
Q6ZQW0