HPSE2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008284Biological processpositive regulation of cell population proliferation
GO_0030198Biological processextracellular matrix organization
GO_0008283Biological processcell population proliferation
GO_0008150Biological processbiological_process
GO_0005615Cellular componentextracellular space
GO_0005886Cellular componentplasma membrane
GO_0031012Cellular componentextracellular matrix
GO_0043395Molecular functionheparan sulfate proteoglycan binding
GO_0030305Molecular functionheparanase activity

IV. Literature review

[source]
Gene nameHPSE2
Protein nameMutant heparanase 2
Heparanase 2
Heparanase 2 (inactive)
Inactive heparanase-2 (Hpa2)
SynonymsHPA2
DescriptionFUNCTION: Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro). .

AccessionsQ2M1H9
ENST00000370549.5 [Q8WWQ2-3]
ENST00000370546.5 [Q8WWQ2-2]
ENST00000370552.8 [Q8WWQ2-1]
ENST00000404542.5
F8S1G9
Q8WWQ2
A0A0A0MSB9
ENST00000628193.2 [Q8WWQ2-4]