HPR | OmnibusX

Name	Number of supported studies	Average coverage
hepatocyte	3 studies	43% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of HPR at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	17857.33	226 / 226	92%	390.47	372 / 406
brain	87%	293.68	2295 / 2642	87%	18.71	611 / 705
heart	98%	2130.15	844 / 861	0%	0	0 / 0
blood vessel	62%	364.02	822 / 1335	0%	0	0 / 0
ovary	56%	80.26	101 / 180	3%	0.13	12 / 430
adipose	50%	177.37	601 / 1204	0%	0	0 / 0
kidney	33%	117.17	29 / 89	5%	1.61	45 / 901
lung	28%	64.60	161 / 578	4%	0.28	42 / 1155
esophagus	24%	43.56	348 / 1445	2%	0.06	3 / 183
breast	23%	80.17	104 / 459	1%	0.13	15 / 1118
prostate	20%	64.65	49 / 245	3%	0.24	15 / 502
stomach	19%	48.29	67 / 359	0%	0.01	1 / 286
intestine	15%	34.96	141 / 966	2%	0.51	10 / 527
uterus	12%	34.22	21 / 170	2%	0.09	8 / 459
muscle	14%	28.86	113 / 803	0%	0	0 / 0
peripheral blood	12%	23.44	112 / 929	0%	0	0 / 0
adrenal gland	3%	9.41	9 / 258	5%	0.32	12 / 230
thymus	8%	53.16	51 / 653	1%	0.03	4 / 605
bladder	5%	2.76	1 / 21	2%	0.10	9 / 504
skin	6%	16.48	103 / 1809	1%	0.06	4 / 472
pancreas	2%	7.87	8 / 328	3%	0.55	5 / 178
spleen	3%	23.51	7 / 241	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0005615	Cellular component	extracellular space
GO_0072562	Cellular component	blood microparticle
GO_0070062	Cellular component	extracellular exosome
GO_0005576	Cellular component	extracellular region
GO_0034366	Cellular component	spherical high-density lipoprotein particle
GO_0004252	Molecular function	serine-type endopeptidase activity
GO_0030492	Molecular function	hemoglobin binding

Gene name	HPR
Protein name	Haptoglobin-related protein
Synonyms
Description	FUNCTION: Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron. .
Accessions	ENST00000540303.7 [P00739-1] ENST00000561690.1 A0A3B3ISM1 P00739 ENST00000649683.1 J3KTC3

HPR report