Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell of proximal tubule | 5 studies | 56% ± 22% | |
| hepatocyte | 5 studies | 81% ± 14% | |
| mature NK T cell | 3 studies | 23% ± 3% | |
| cholangiocyte | 3 studies | 43% ± 21% | |
| endothelial cell | 3 studies | 33% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| liver | 3 studies | 36% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 56169.96 | 226 / 226 | 96% | 1119.80 | 391 / 406 |
| kidney | 100% | 16168.06 | 89 / 89 | 66% | 12.27 | 593 / 901 |
| ovary | 98% | 274.78 | 177 / 180 | 65% | 3.21 | 279 / 430 |
| pancreas | 95% | 132.13 | 312 / 328 | 42% | 1.00 | 75 / 178 |
| prostate | 85% | 153.11 | 209 / 245 | 38% | 0.83 | 189 / 502 |
| lung | 94% | 129.95 | 545 / 578 | 24% | 1.87 | 282 / 1155 |
| adrenal gland | 100% | 316.15 | 258 / 258 | 18% | 1.61 | 42 / 230 |
| bladder | 95% | 235.29 | 20 / 21 | 20% | 0.85 | 99 / 504 |
| uterus | 79% | 186.61 | 135 / 170 | 24% | 1.37 | 111 / 459 |
| blood vessel | 99% | 386.08 | 1327 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 93% | 153.74 | 223 / 241 | 0% | 0 | 0 / 0 |
| esophagus | 60% | 66.44 | 861 / 1445 | 30% | 0.61 | 54 / 183 |
| breast | 69% | 73.82 | 316 / 459 | 11% | 1.55 | 124 / 1118 |
| intestine | 66% | 59.44 | 638 / 966 | 12% | 1.19 | 63 / 527 |
| adipose | 77% | 96.06 | 923 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 58% | 102.12 | 209 / 359 | 17% | 0.45 | 50 / 286 |
| heart | 74% | 103.00 | 641 / 861 | 0% | 0 | 0 / 0 |
| muscle | 67% | 69.38 | 537 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 64% | 465.97 | 595 / 929 | 0% | 0 | 0 / 0 |
| thymus | 52% | 47.23 | 341 / 653 | 10% | 0.15 | 62 / 605 |
| brain | 14% | 11.25 | 367 / 2642 | 42% | 2.57 | 296 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 41% | 0.67 | 12 / 29 |
| skin | 31% | 43.43 | 562 / 1809 | 6% | 0.29 | 28 / 472 |
| eye | 0% | 0 | 0 / 0 | 16% | 0.41 | 13 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.09 | 3 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006559 | Biological process | L-phenylalanine catabolic process |
| GO_0006572 | Biological process | tyrosine catabolic process |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0003868 | Molecular function | 4-hydroxyphenylpyruvate dioxygenase activity |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | HPD |
| Protein name | 4-hydroxyphenylpyruvate dioxygenase 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase) |
| Synonyms | PPD |
| Description | FUNCTION: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism. . FUNCTION: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism. . |
| Accessions | ENST00000543163.5 [P32754-2] ENST00000289004.8 P32754 A0A0B4J1R4 |
