HFM1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	9 studies	31% ± 12%	Explore
astrocyte	7 studies	34% ± 15%	Explore
GABAergic neuron	6 studies	34% ± 16%	Explore
glutamatergic neuron	4 studies	40% ± 11%	Explore
endothelial cell	3 studies	38% ± 12%	Explore
neuron	3 studies	23% ± 3%	Explore
interneuron	3 studies	46% ± 19%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	6 studies	28% ± 14%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	98%	266.97	2584 / 2642	82%	2.61	580 / 705
thymus	100%	437.39	652 / 653	24%	0.47	147 / 605
ovary	100%	718.49	180 / 180	15%	0.33	65 / 430
uterus	98%	334.12	166 / 170	11%	0.23	50 / 459
kidney	96%	164.08	85 / 89	6%	0.16	57 / 901
prostate	94%	147.20	231 / 245	6%	0.09	32 / 502
breast	93%	109.29	427 / 459	2%	0.05	24 / 1118
muscle	95%	155.39	761 / 803	0%	0	0 / 0
pancreas	86%	107.10	281 / 328	4%	0.09	8 / 178
adipose	90%	111.20	1084 / 1204	0%	0	0 / 0
adrenal gland	76%	91.90	197 / 258	12%	0.21	28 / 230
bladder	86%	129.57	18 / 21	3%	0.05	13 / 504
heart	87%	98.48	746 / 861	0%	0	0 / 0
spleen	86%	84.39	207 / 241	0%	0	0 / 0
intestine	77%	125.91	741 / 966	1%	0.01	4 / 527
esophagus	67%	98.47	970 / 1445	5%	0.08	10 / 183
lung	63%	52.12	363 / 578	6%	0.11	73 / 1155
stomach	48%	67.31	173 / 359	3%	0.05	10 / 286
blood vessel	37%	33.70	491 / 1335	0%	0	0 / 0
skin	16%	12.11	289 / 1809	20%	0.37	96 / 472
eye	0%	0	0 / 0	10%	0.20	8 / 80
tonsil	0%	0	0 / 0	7%	0.13	3 / 45
liver	1%	0.49	2 / 226	1%	0.02	4 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1