I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 4 studies | 23% ± 6% | |
| GABAergic neuron | 3 studies | 37% ± 1% | |
| glutamatergic neuron | 3 studies | 36% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte precursor cell | 4 studies | 23% ± 6% | |
| GABAergic neuron | 3 studies | 37% ± 1% | |
| glutamatergic neuron | 3 studies | 36% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 28% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 99% | 1197.22 | 243 / 245 | 99% | 24.35 | 499 / 502 |
| esophagus | 99% | 1585.43 | 1434 / 1445 | 98% | 27.35 | 179 / 183 |
| thymus | 99% | 872.40 | 648 / 653 | 96% | 14.74 | 582 / 605 |
| ovary | 99% | 1267.49 | 179 / 180 | 95% | 19.95 | 407 / 430 |
| kidney | 100% | 1136.45 | 89 / 89 | 92% | 10.75 | 833 / 901 |
| pancreas | 98% | 498.13 | 321 / 328 | 94% | 16.71 | 168 / 178 |
| stomach | 99% | 711.13 | 357 / 359 | 91% | 12.03 | 260 / 286 |
| lung | 99% | 905.57 | 570 / 578 | 91% | 14.36 | 1046 / 1155 |
| uterus | 100% | 1345.34 | 170 / 170 | 88% | 22.32 | 406 / 459 |
| intestine | 99% | 693.00 | 961 / 966 | 88% | 11.96 | 463 / 527 |
| brain | 92% | 861.72 | 2441 / 2642 | 94% | 16.76 | 665 / 705 |
| breast | 99% | 826.08 | 453 / 459 | 86% | 22.55 | 958 / 1118 |
| bladder | 100% | 624.52 | 21 / 21 | 82% | 14.60 | 412 / 504 |
| adrenal gland | 98% | 1022.70 | 254 / 258 | 76% | 11.60 | 174 / 230 |
| skin | 93% | 470.92 | 1684 / 1809 | 73% | 10.82 | 344 / 472 |
| liver | 77% | 291.03 | 175 / 226 | 35% | 3.32 | 144 / 406 |
| spleen | 100% | 1078.39 | 241 / 241 | 0% | 0 | 0 / 0 |
| heart | 98% | 778.51 | 843 / 861 | 0% | 0 | 0 / 0 |
| adipose | 98% | 731.55 | 1178 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 28.38 | 43 / 45 |
| blood vessel | 95% | 593.45 | 1272 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 81% | 580.61 | 753 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 69% | 5.97 | 20 / 29 |
| muscle | 49% | 155.03 | 396 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 39% | 3.90 | 31 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016567 | Biological process | protein ubiquitination |
| GO_0002244 | Biological process | hematopoietic progenitor cell differentiation |
| GO_0006511 | Biological process | ubiquitin-dependent protein catabolic process |
| GO_0009617 | Biological process | response to bacterium |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0061630 | Molecular function | ubiquitin protein ligase activity |
| Gene name | HERC6 |
| Protein name | Probable E3 ubiquitin-protein ligase HERC6 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 6) (HECT-type E3 ubiquitin transferase HERC6) HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| Synonyms | |
| Description | FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. . |
| Accessions | ENST00000504905.5 ENST00000264346.12 [Q8IVU3-1] ENST00000380265.9 [Q8IVU3-2] Q8IVU3 ENST00000502870.1 D6RCT4 H0Y9U0 |
