HEPHL1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HEPHL1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HEPHL1 at tissue level.

III. Associated gene sets

GO_0006879Biological processintracellular iron ion homeostasis
GO_0006826Biological processiron ion transport
GO_0006825Biological processcopper ion transport
GO_0005886Cellular componentplasma membrane
GO_0004322Molecular functionferroxidase activity
GO_0005507Molecular functioncopper ion binding

IV. Literature review

[source]
Gene nameHEPHL1
Protein nameFerroxidase HEPHL1 (EC 1.16.3.1) (Hephaestin-like protein 1)
Synonyms
DescriptionFUNCTION: Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species . May be involved in the regulation of intracellular iron content . .

AccessionsQ6MZM0
ENST00000315765.10