Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 7 studies | 34% ± 15% | |
| goblet cell | 5 studies | 21% ± 5% | |
| brush cell | 4 studies | 23% ± 7% | |
| enterocyte | 4 studies | 23% ± 2% | |
| epithelial cell | 4 studies | 26% ± 13% | |
| smooth muscle cell | 3 studies | 24% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestine | 3 studies | 19% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 100% | 11303.63 | 964 / 966 | 95% | 95.76 | 502 / 527 |
| lung | 98% | 2372.77 | 567 / 578 | 66% | 11.98 | 764 / 1155 |
| prostate | 92% | 2320.52 | 226 / 245 | 68% | 8.30 | 342 / 502 |
| breast | 77% | 1274.81 | 352 / 459 | 82% | 13.49 | 915 / 1118 |
| brain | 79% | 1586.74 | 2096 / 2642 | 78% | 14.89 | 552 / 705 |
| adrenal gland | 100% | 3639.36 | 257 / 258 | 47% | 7.56 | 108 / 230 |
| stomach | 51% | 2024.98 | 182 / 359 | 93% | 76.55 | 265 / 286 |
| esophagus | 71% | 3284.69 | 1030 / 1445 | 70% | 24.04 | 128 / 183 |
| bladder | 90% | 2413.48 | 19 / 21 | 50% | 32.18 | 252 / 504 |
| ovary | 98% | 3011.57 | 176 / 180 | 32% | 3.11 | 137 / 430 |
| uterus | 98% | 4240.97 | 166 / 170 | 30% | 9.94 | 139 / 459 |
| kidney | 49% | 800.71 | 44 / 89 | 52% | 7.16 | 465 / 901 |
| blood vessel | 100% | 8217.49 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| thymus | 73% | 961.61 | 474 / 653 | 25% | 2.69 | 152 / 605 |
| spleen | 92% | 1470.86 | 221 / 241 | 0% | 0 | 0 / 0 |
| pancreas | 2% | 14.66 | 5 / 328 | 89% | 30.85 | 158 / 178 |
| skin | 66% | 1372.44 | 1198 / 1809 | 17% | 2.56 | 78 / 472 |
| heart | 82% | 2220.89 | 709 / 861 | 0% | 0 | 0 / 0 |
| adipose | 71% | 1129.12 | 858 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 2.32 | 11 / 45 |
| liver | 1% | 9.46 | 2 / 226 | 10% | 0.93 | 42 / 406 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.37 | 3 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.21 | 1 / 29 |
| peripheral blood | 2% | 17.95 | 15 / 929 | 0% | 0 | 0 / 0 |
| muscle | 1% | 8.46 | 7 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006826 | Biological process | iron ion transport |
| GO_0006825 | Biological process | copper ion transport |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0004322 | Molecular function | ferroxidase activity |
| GO_0016491 | Molecular function | oxidoreductase activity |
| GO_0008198 | Molecular function | ferrous iron binding |
| GO_0005507 | Molecular function | copper ion binding |
| Gene name | HEPH |
| Protein name | Hephaestin Hephaestin (EC 1.-.-.-) ferroxidase (EC 1.16.3.1) |
| Synonyms | KIAA0698 hCG_18329 UNQ2562/PRO6242 |
| Description | FUNCTION: May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. Implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1. |
| Accessions | ENST00000684625.1 A0A0C4DG76 ENST00000425114.2 A0A804HIE6 ENST00000336279.9 [Q9BQS7-4] ENST00000441993 ENST00000429547.6 A0A804HJ33 ENST00000684603.1 ENST00000519389.6 [Q9BQS7-1] E7ES21 ENST00000441993.7 [Q9BQS7-2] A0A804HK72 ENST00000682927.1 A0A804HKF4 F8WBZ8 Q5JZ07 A0A804HJ98 Q1HE23 ENST00000684042.1 ENST00000343002.7 [Q9BQS7-1] Q5JZ08 ENST00000683049.1 ENST00000419594.6 ENST00000682362.1 Q9BQS7 ENST00000458621.6 |
