I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 21% ± 4% | |
| GABAergic neuron | 3 studies | 31% ± 3% | |
| glutamatergic neuron | 3 studies | 41% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 21% ± 4% | |
| GABAergic neuron | 3 studies | 31% ± 3% | |
| glutamatergic neuron | 3 studies | 41% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 29% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1306.66 | 1445 / 1445 | 100% | 36.26 | 183 / 183 |
| prostate | 100% | 1468.91 | 245 / 245 | 100% | 26.37 | 502 / 502 |
| stomach | 100% | 1218.92 | 359 / 359 | 100% | 28.58 | 286 / 286 |
| breast | 100% | 1481.03 | 459 / 459 | 100% | 32.99 | 1117 / 1118 |
| brain | 100% | 1597.85 | 2638 / 2642 | 100% | 31.16 | 705 / 705 |
| thymus | 100% | 1458.47 | 653 / 653 | 100% | 17.77 | 604 / 605 |
| uterus | 100% | 1346.27 | 170 / 170 | 100% | 20.97 | 458 / 459 |
| liver | 100% | 948.86 | 226 / 226 | 100% | 14.94 | 405 / 406 |
| pancreas | 100% | 892.80 | 327 / 328 | 100% | 18.01 | 178 / 178 |
| kidney | 100% | 1401.97 | 89 / 89 | 100% | 18.43 | 898 / 901 |
| intestine | 100% | 1380.34 | 966 / 966 | 100% | 27.54 | 525 / 527 |
| bladder | 100% | 1354.43 | 21 / 21 | 100% | 21.78 | 502 / 504 |
| ovary | 100% | 1335.14 | 180 / 180 | 100% | 19.99 | 428 / 430 |
| skin | 100% | 2084.98 | 1809 / 1809 | 99% | 27.95 | 469 / 472 |
| lung | 99% | 1063.73 | 573 / 578 | 100% | 22.44 | 1155 / 1155 |
| adrenal gland | 100% | 1492.95 | 258 / 258 | 99% | 16.90 | 228 / 230 |
| adipose | 100% | 1342.93 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 21.10 | 29 / 29 |
| muscle | 100% | 2639.00 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1364.00 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 22.70 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 12.89 | 1 / 1 |
| blood vessel | 100% | 963.93 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 22.65 | 79 / 80 |
| heart | 95% | 1139.27 | 821 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 74% | 1065.01 | 692 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006412 | Biological process | translation |
| GO_0045727 | Biological process | positive regulation of translation |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005525 | Molecular function | GTP binding |
| GO_0097177 | Molecular function | mitochondrial ribosome binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | GUF1 |
| Protein name | Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase) GTP binding elongation factor GUF1 |
| Synonyms | |
| Description | FUNCTION: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. . |
| Accessions | ENST00000281543.6 D6RBJ0 Q8N442 ENST00000513775.1 |
