GSTA3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GSTA3 at tissue level.

III. Associated gene sets

GO_0006805Biological processxenobiotic metabolic process
GO_0006629Biological processlipid metabolic process
GO_0006749Biological processglutathione metabolic process
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0004364Molecular functionglutathione transferase activity

IV. Literature review

[source]
Gene nameGSTA3
Protein nameglutathione transferase (EC 2.5.1.18)
Glutathione S-transferase (EC 2.5.1.18)
Glutathione S-transferase A3 (EC 2.5.1.18) (GST class-alpha member 3) (Glutathione S-transferase A3-3)
SynonymshCG_21946
DescriptionFUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)-pregnene-3,20-dione, precursors to testosterone and progesterone, respectively. Has substantial activity toward aflatoxin B1-8,9-epoxide (By similarity). .

AccessionsQ16772
Q5JW84
ENST00000211122.4
ENST00000431899.2
ENST00000370968.5
Q5JW85