Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte precursor cell | 14 studies | 73% ± 20% | |
glutamatergic neuron | 12 studies | 68% ± 23% | |
GABAergic neuron | 11 studies | 58% ± 20% | |
astrocyte | 8 studies | 33% ± 22% | |
oligodendrocyte | 6 studies | 35% ± 22% | |
neuron | 5 studies | 33% ± 12% | |
interneuron | 5 studies | 53% ± 26% | |
endothelial cell | 4 studies | 46% ± 17% | |
microglial cell | 4 studies | 39% ± 23% | |
amacrine cell | 4 studies | 39% ± 11% | |
GABAergic interneuron | 3 studies | 68% ± 8% | |
GABAergic amacrine cell | 3 studies | 49% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 96% | 462.61 | 2541 / 2642 | 32% | 1.07 | 226 / 705 |
uterus | 62% | 110.21 | 105 / 170 | 3% | 0.05 | 14 / 459 |
bladder | 57% | 50.71 | 12 / 21 | 1% | 0.03 | 7 / 504 |
prostate | 36% | 32.94 | 88 / 245 | 19% | 1.15 | 94 / 502 |
adrenal gland | 27% | 62.83 | 69 / 258 | 20% | 1.10 | 46 / 230 |
blood vessel | 45% | 39.12 | 597 / 1335 | 0% | 0 | 0 / 0 |
adipose | 32% | 26.79 | 380 / 1204 | 0% | 0 | 0 / 0 |
ovary | 25% | 26.36 | 45 / 180 | 5% | 0.07 | 20 / 430 |
breast | 27% | 20.01 | 123 / 459 | 2% | 0.08 | 26 / 1118 |
lung | 12% | 12.73 | 71 / 578 | 2% | 0.05 | 27 / 1155 |
thymus | 12% | 7.51 | 76 / 653 | 0% | 0.01 | 2 / 605 |
esophagus | 10% | 8.94 | 145 / 1445 | 1% | 0.01 | 2 / 183 |
skin | 3% | 1.35 | 46 / 1809 | 4% | 0.17 | 19 / 472 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.05 | 1 / 29 |
stomach | 1% | 0.60 | 5 / 359 | 1% | 0.02 | 4 / 286 |
pancreas | 1% | 0.30 | 2 / 328 | 2% | 0.04 | 3 / 178 |
liver | 0% | 0 | 0 / 226 | 2% | 0.05 | 7 / 406 |
intestine | 2% | 0.80 | 15 / 966 | 0% | 0 | 0 / 527 |
eye | 0% | 0 | 0 / 0 | 1% | 0.01 | 1 / 80 |
kidney | 0% | 0 | 0 / 89 | 1% | 0.04 | 8 / 901 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007605 | Biological process | sensory perception of sound |
GO_0014050 | Biological process | negative regulation of glutamate secretion |
GO_0061564 | Biological process | axon development |
GO_0007196 | Biological process | adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway |
GO_0007216 | Biological process | G protein-coupled glutamate receptor signaling pathway |
GO_0051966 | Biological process | regulation of synaptic transmission, glutamatergic |
GO_0070085 | Biological process | glycosylation |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0001662 | Biological process | behavioral fear response |
GO_0043235 | Cellular component | receptor complex |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0043198 | Cellular component | dendritic shaft |
GO_0030425 | Cellular component | dendrite |
GO_0048786 | Cellular component | presynaptic active zone |
GO_0032279 | Cellular component | asymmetric synapse |
GO_0005938 | Cellular component | cell cortex |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0030424 | Cellular component | axon |
GO_0008066 | Molecular function | glutamate receptor activity |
GO_0070905 | Molecular function | serine binding |
GO_0046983 | Molecular function | protein dimerization activity |
GO_0001642 | Molecular function | group III metabotropic glutamate receptor activity |
GO_0010855 | Molecular function | adenylate cyclase inhibitor activity |
Gene name | GRM7 |
Protein name | Metabotropic glutamate receptor 7 (mGluR7) GRM7 protein Glutamate metabotropic receptor 7 Alternative protein GRM7 |
Synonyms | GPRC1G MGLUR7 |
Description | FUNCTION: G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development . Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits . . |
Accessions | F8WCR9 L8E797 ENST00000440923.7 ENST00000467425.5 [Q14831-2] ENST00000448328.6 ENST00000706912.1 F8WAW6 C9JU97 ENST00000486284.5 [Q14831-2] A0A9L9PY31 ENST00000445087.1 ENST00000706913.1 Q14831 ENST00000389335.7 [Q14831-4] B9EGG9 ENST00000389336.8 [Q14831-5] H7C3K2 A0A9L9PXG5 C9JMT3 ENST00000357716.9 [Q14831-1] B7ZKK0 ENST00000443259.1 ENST00000435689.5 |