GRM7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007605Biological processsensory perception of sound
GO_0014050Biological processnegative regulation of glutamate secretion
GO_0061564Biological processaxon development
GO_0007196Biological processadenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
GO_0007216Biological processG protein-coupled glutamate receptor signaling pathway
GO_0051966Biological processregulation of synaptic transmission, glutamatergic
GO_0070085Biological processglycosylation
GO_0007268Biological processchemical synaptic transmission
GO_0001662Biological processbehavioral fear response
GO_0043235Cellular componentreceptor complex
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0043198Cellular componentdendritic shaft
GO_0030425Cellular componentdendrite
GO_0048786Cellular componentpresynaptic active zone
GO_0032279Cellular componentasymmetric synapse
GO_0005938Cellular componentcell cortex
GO_0045211Cellular componentpostsynaptic membrane
GO_0030424Cellular componentaxon
GO_0008066Molecular functionglutamate receptor activity
GO_0070905Molecular functionserine binding
GO_0046983Molecular functionprotein dimerization activity
GO_0001642Molecular functiongroup III metabotropic glutamate receptor activity
GO_0010855Molecular functionadenylate cyclase inhibitor activity

IV. Literature review

[source]
Gene nameGRM7
Protein nameMetabotropic glutamate receptor 7 (mGluR7)
GRM7 protein
Glutamate metabotropic receptor 7
Alternative protein GRM7
SynonymsGPRC1G
MGLUR7
DescriptionFUNCTION: G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development . Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits . .

AccessionsF8WCR9
L8E797
ENST00000440923.7
ENST00000467425.5 [Q14831-2]
ENST00000448328.6
ENST00000706912.1
F8WAW6
C9JU97
ENST00000486284.5 [Q14831-2]
A0A9L9PY31
ENST00000445087.1
ENST00000706913.1
Q14831
ENST00000389335.7 [Q14831-4]
B9EGG9
ENST00000389336.8 [Q14831-5]
H7C3K2
A0A9L9PXG5
C9JMT3
ENST00000357716.9 [Q14831-1]
B7ZKK0
ENST00000443259.1
ENST00000435689.5