GPX5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GPX5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GPX5 at tissue level.

III. Associated gene sets

GO_0034599Biological processcellular response to oxidative stress
GO_0006629Biological processlipid metabolic process
GO_0098869Biological processcellular oxidant detoxification
GO_0005576Cellular componentextracellular region
GO_0004602Molecular functionglutathione peroxidase activity

IV. Literature review

[source]
Gene nameGPX5
Protein nameGlutathione peroxidase
Epididymal secretory glutathione peroxidase (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Glutathione peroxidase 5) (GPx-5) (GSHPx-5)
SynonymshCG_22448
HEL-S-75p
DescriptionFUNCTION: Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.

AccessionsO75715
V9HWN8
ENST00000551639.1 [O75715-2]
ENST00000550775.5 [O75715-1]
ENST00000412168.7 [O75715-1]
ENST00000469384.1 [O75715-2]