I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 21% ± 3% | |
| ciliated cell | 3 studies | 19% ± 4% | |
| dendritic cell | 3 studies | 17% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 21% ± 3% | |
| ciliated cell | 3 studies | 19% ± 4% | |
| dendritic cell | 3 studies | 17% ± 1% |
Insufficient scRNA-seq data for expression of GPR137 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 3044.62 | 2642 / 2642 | 100% | 48.89 | 705 / 705 |
| esophagus | 100% | 1733.92 | 1445 / 1445 | 100% | 21.54 | 183 / 183 |
| ovary | 100% | 1239.17 | 180 / 180 | 100% | 41.26 | 430 / 430 |
| thymus | 100% | 2406.13 | 653 / 653 | 100% | 29.67 | 605 / 605 |
| uterus | 100% | 1727.01 | 170 / 170 | 100% | 29.92 | 458 / 459 |
| skin | 100% | 1387.61 | 1808 / 1809 | 100% | 38.74 | 471 / 472 |
| liver | 100% | 1233.08 | 226 / 226 | 100% | 24.65 | 404 / 406 |
| prostate | 100% | 2182.18 | 245 / 245 | 99% | 35.40 | 499 / 502 |
| adrenal gland | 100% | 2123.81 | 258 / 258 | 99% | 35.93 | 228 / 230 |
| kidney | 100% | 2141.22 | 89 / 89 | 99% | 28.46 | 893 / 901 |
| intestine | 100% | 1549.74 | 966 / 966 | 99% | 20.31 | 520 / 527 |
| breast | 100% | 1408.11 | 459 / 459 | 98% | 29.28 | 1098 / 1118 |
| stomach | 100% | 1472.36 | 359 / 359 | 98% | 21.05 | 280 / 286 |
| lung | 100% | 1413.95 | 576 / 578 | 98% | 24.23 | 1131 / 1155 |
| bladder | 100% | 1836.48 | 21 / 21 | 97% | 26.26 | 489 / 504 |
| pancreas | 91% | 622.64 | 299 / 328 | 99% | 24.95 | 176 / 178 |
| adipose | 100% | 1388.79 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 47.10 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 32.24 | 29 / 29 |
| spleen | 100% | 1790.12 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 30.02 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 49.80 | 1 / 1 |
| blood vessel | 100% | 1334.78 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 1283.43 | 851 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 96% | 1000.41 | 896 / 929 | 0% | 0 | 0 / 0 |
| muscle | 90% | 639.44 | 721 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006914 | Biological process | autophagy |
| GO_0010506 | Biological process | regulation of autophagy |
| GO_1904263 | Biological process | positive regulation of TORC1 signaling |
| GO_0045779 | Biological process | negative regulation of bone resorption |
| GO_0045671 | Biological process | negative regulation of osteoclast differentiation |
| GO_0005765 | Cellular component | lysosomal membrane |
| Gene name | GPR137 |
| Protein name | Alternative protein GPR137 Integral membrane protein GPR137 (Transmembrane 7 superfamily member 1-like 1 protein) G protein-coupled receptor 137 |
| Synonyms | C11orf4 TM7SF1L1 GPR137A |
| Description | FUNCTION: Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes . May play a role in autophagy . .; FUNCTION: May activate Wnt/beta-catenin signaling to modulate epithelial cell function. . |
| Accessions | F5H0Q1 ENST00000536282.1 ENST00000543383.5 ENST00000536667.5 F5H1V9 ENST00000313074.7 [Q96N19-1] ENST00000542190.5 L8EA54 ENST00000538032.5 ENST00000546139.5 ENST00000539833.5 Q96N19 H0YGJ1 F5H1T3 F5H7S0 F5H4R8 ENST00000377702.8 [Q96N19-3] F5H097 ENST00000535675.5 F5GXI8 F5H6Y8 ENST00000540370.1 ENST00000538244.1 ENST00000438980.7 [Q96N19-2] ENST00000411458.5 [Q96N19-1] ENST00000541952.1 F5H234 F5GXD9 F5GXW8 ENST00000546201.5 |
