Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 30% ± 11% | |
| endothelial cell | 3 studies | 17% ± 0% | |
| ciliated cell | 3 studies | 19% ± 2% | |
| fibroblast | 3 studies | 20% ± 3% | |
| GABAergic neuron | 3 studies | 23% ± 5% | |
| glutamatergic neuron | 3 studies | 31% ± 5% | |
| dendritic cell | 3 studies | 24% ± 8% | |
| basal cell | 3 studies | 26% ± 6% | |
| astrocyte | 3 studies | 21% ± 5% | |
| oligodendrocyte | 3 studies | 17% ± 1% | |
| hepatocyte | 3 studies | 44% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 25% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1822.97 | 1445 / 1445 | 100% | 16.70 | 183 / 183 |
| ovary | 100% | 2517.59 | 180 / 180 | 100% | 16.03 | 430 / 430 |
| pancreas | 100% | 2162.48 | 328 / 328 | 100% | 15.28 | 178 / 178 |
| breast | 100% | 2429.14 | 459 / 459 | 100% | 22.16 | 1117 / 1118 |
| lung | 100% | 3223.92 | 578 / 578 | 100% | 28.66 | 1153 / 1155 |
| liver | 100% | 6993.99 | 226 / 226 | 100% | 53.96 | 405 / 406 |
| intestine | 100% | 1908.95 | 966 / 966 | 100% | 11.51 | 525 / 527 |
| bladder | 100% | 2318.33 | 21 / 21 | 100% | 19.94 | 502 / 504 |
| uterus | 100% | 2620.27 | 170 / 170 | 100% | 18.77 | 457 / 459 |
| prostate | 100% | 2285.06 | 245 / 245 | 99% | 18.11 | 499 / 502 |
| brain | 99% | 1553.63 | 2624 / 2642 | 100% | 14.79 | 705 / 705 |
| stomach | 100% | 1843.70 | 359 / 359 | 99% | 12.68 | 284 / 286 |
| skin | 100% | 2505.47 | 1807 / 1809 | 99% | 23.12 | 469 / 472 |
| thymus | 100% | 2766.25 | 653 / 653 | 99% | 16.83 | 598 / 605 |
| kidney | 100% | 2151.76 | 89 / 89 | 98% | 19.09 | 883 / 901 |
| adrenal gland | 100% | 2360.75 | 258 / 258 | 90% | 10.01 | 206 / 230 |
| adipose | 100% | 2456.23 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 8.17 | 29 / 29 |
| spleen | 100% | 1791.16 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 16.32 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.64 | 1 / 1 |
| blood vessel | 100% | 1846.89 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 1766.38 | 802 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 17.87 | 79 / 80 |
| heart | 99% | 1542.69 | 850 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 84% | 770.40 | 781 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0017187 | Biological process | peptidyl-glutamic acid carboxylation |
| GO_0036211 | Biological process | protein modification process |
| GO_0007596 | Biological process | blood coagulation |
| GO_0042373 | Biological process | vitamin K metabolic process |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0008488 | Molecular function | gamma-glutamyl carboxylase activity |
| GO_0019842 | Molecular function | vitamin binding |
| Gene name | GGCX |
| Protein name | Gamma-glutamyl carboxylase Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase) |
| Synonyms | GC hCG_34601 |
| Description | FUNCTION: Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide . Catalyzes gamma-carboxylation of various proteins, such as blood coagulation factors (F2, F7, F9 and F10), osteocalcin (BGLAP) or matrix Gla protein (MGP) . . |
| Accessions | A0A8I5KY98 ENST00000688205.1 A0A8I5QJS0 A7YA96 ENST00000496962.2 ENST00000689576.1 ENST00000691410.1 A0A8I5KV68 ENST00000233838.9 [P38435-1] A0A8I5KXY4 A0A8I5QJ91 ENST00000691348.1 A0A8I5KT68 ENST00000690595.1 ENST00000421496.5 ENST00000690108.1 ENST00000693287.1 ENST00000689276.1 ENST00000430215.7 [P38435-2] F8WB98 A0A8I5QKY1 ENST00000428479.3 P38435 A0A8I5KZ18 A0A8I5QJA4 ENST00000693681.1 A0A8I5KXJ8 ENST00000481541.1 F8WCF0 ENST00000690468.1 A0A8I5KXQ8 |
