GDPD2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GDPD2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GDPD2 at tissue level.

III. Associated gene sets

GO_0006629Biological processlipid metabolic process
GO_0045669Biological processpositive regulation of osteoblast differentiation
GO_0007015Biological processactin filament organization
GO_0005737Cellular componentcytoplasm
GO_0030027Cellular componentlamellipodium
GO_0005886Cellular componentplasma membrane
GO_0005884Cellular componentactin filament
GO_0008889Molecular functionglycerophosphodiester phosphodiesterase activity
GO_0047394Molecular functionglycerophosphoinositol inositolphosphodiesterase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameGDPD2
Protein nameGlycerophosphoinositol inositolphosphodiesterase GDPD2 (EC 3.1.4.43) (Glycerophosphodiester phosphodiesterase 3) (Glycerophosphodiester phosphodiesterase domain-containing protein 2) (Osteoblast differentiation promoting factor)
SynonymsUNQ1935/PRO4418
OBDPF
GDE3
DescriptionFUNCTION: Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4-phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity). .

AccessionsENST00000453994.6 [Q9HCC8-3]
ENST00000374382.4 [Q9HCC8-1]
Q9HCC8
ENST00000536730.5 [Q9HCC8-2]
ENST00000538649.5 [Q9HCC8-2]