Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 25% ± 10% | |
| enterocyte | 5 studies | 20% ± 4% | |
| mucus secreting cell | 4 studies | 25% ± 4% | |
| squamous epithelial cell | 3 studies | 51% ± 19% | |
| respiratory goblet cell | 3 studies | 27% ± 10% |
Insufficient scRNA-seq data for expression of GCNT3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 75% | 740.80 | 270 / 359 | 86% | 47.87 | 247 / 286 |
| kidney | 98% | 710.01 | 87 / 89 | 63% | 10.16 | 567 / 901 |
| intestine | 64% | 3704.73 | 614 / 966 | 90% | 59.63 | 475 / 527 |
| pancreas | 55% | 132.04 | 179 / 328 | 87% | 94.49 | 154 / 178 |
| esophagus | 40% | 589.08 | 579 / 1445 | 61% | 54.84 | 112 / 183 |
| lung | 27% | 38.51 | 155 / 578 | 53% | 21.05 | 612 / 1155 |
| thymus | 66% | 94.02 | 434 / 653 | 13% | 1.33 | 78 / 605 |
| prostate | 55% | 155.60 | 135 / 245 | 2% | 0.10 | 8 / 502 |
| bladder | 19% | 43.48 | 4 / 21 | 33% | 12.76 | 168 / 504 |
| adrenal gland | 47% | 85.49 | 121 / 258 | 3% | 0.32 | 6 / 230 |
| liver | 15% | 20.23 | 34 / 226 | 27% | 5.21 | 108 / 406 |
| uterus | 13% | 46.31 | 22 / 170 | 27% | 9.18 | 126 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 40% | 9.05 | 18 / 45 |
| ovary | 7% | 9.71 | 12 / 180 | 11% | 0.96 | 46 / 430 |
| peripheral blood | 14% | 38.69 | 132 / 929 | 0% | 0 | 0 / 0 |
| skin | 9% | 9.31 | 171 / 1809 | 1% | 0.09 | 3 / 472 |
| breast | 3% | 32.98 | 16 / 459 | 3% | 0.59 | 30 / 1118 |
| heart | 2% | 1.50 | 18 / 861 | 0% | 0 | 0 / 0 |
| spleen | 2% | 1.24 | 5 / 241 | 0% | 0 | 0 / 0 |
| brain | 1% | 0.61 | 26 / 2642 | 0% | 0 | 0 / 705 |
| adipose | 1% | 1.10 | 9 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.90 | 3 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.27 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0005975 | Biological process | carbohydrate metabolic process |
| GO_0016266 | Biological process | O-glycan processing |
| GO_0060993 | Biological process | kidney morphogenesis |
| GO_0048729 | Biological process | tissue morphogenesis |
| GO_0006493 | Biological process | protein O-linked glycosylation |
| GO_0050892 | Biological process | intestinal absorption |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0016020 | Cellular component | membrane |
| GO_0008375 | Molecular function | acetylglucosaminyltransferase activity |
| GO_0003829 | Molecular function | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity |
| GO_0106325 | Molecular function | acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity |
| GO_0106326 | Molecular function | acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity |
| GO_0008109 | Molecular function | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity |
| Gene name | GCNT3 |
| Protein name | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT) Glucosaminyl (N-acetyl) transferase 3, mucin type |
| Synonyms | |
| Description | FUNCTION: Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. . |
| Accessions | ENST00000559189.5 H0YMW7 H0YNA3 O95395 ENST00000559626.1 ENST00000559200.1 ENST00000396065.3 ENST00000560585.5 H0YM40 |
