I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 23% ± 7% | |
| astrocyte | 3 studies | 26% ± 3% | |
| hepatocyte | 3 studies | 29% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 23% ± 7% | |
| astrocyte | 3 studies | 26% ± 3% | |
| hepatocyte | 3 studies | 29% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 4189.84 | 226 / 226 | 100% | 40.64 | 406 / 406 |
| prostate | 100% | 1484.83 | 245 / 245 | 100% | 31.51 | 502 / 502 |
| brain | 100% | 1092.73 | 2635 / 2642 | 100% | 38.76 | 705 / 705 |
| skin | 100% | 993.79 | 1808 / 1809 | 100% | 26.76 | 471 / 472 |
| thymus | 100% | 1358.42 | 653 / 653 | 100% | 21.83 | 603 / 605 |
| uterus | 100% | 1284.63 | 170 / 170 | 100% | 22.20 | 457 / 459 |
| ovary | 100% | 1623.32 | 180 / 180 | 100% | 24.00 | 428 / 430 |
| esophagus | 100% | 1324.12 | 1445 / 1445 | 99% | 13.94 | 182 / 183 |
| breast | 100% | 1565.78 | 459 / 459 | 99% | 24.21 | 1111 / 1118 |
| kidney | 100% | 1458.67 | 89 / 89 | 99% | 15.87 | 892 / 901 |
| pancreas | 99% | 858.91 | 326 / 328 | 99% | 14.95 | 177 / 178 |
| bladder | 100% | 1409.24 | 21 / 21 | 99% | 21.46 | 498 / 504 |
| adrenal gland | 100% | 1595.19 | 258 / 258 | 99% | 18.14 | 227 / 230 |
| intestine | 100% | 1241.06 | 966 / 966 | 99% | 20.68 | 520 / 527 |
| lung | 99% | 981.78 | 575 / 578 | 99% | 17.68 | 1143 / 1155 |
| stomach | 100% | 1383.31 | 359 / 359 | 98% | 17.26 | 281 / 286 |
| adipose | 100% | 1401.43 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 31.12 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 45.09 | 29 / 29 |
| spleen | 100% | 1334.18 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 26.90 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.21 | 1 / 1 |
| blood vessel | 100% | 1186.93 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 1389.47 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 96% | 1313.43 | 829 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 96% | 992.69 | 889 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0046949 | Biological process | fatty-acyl-CoA biosynthetic process |
| GO_0006568 | Biological process | tryptophan metabolic process |
| GO_0033539 | Biological process | fatty acid beta-oxidation using acyl-CoA dehydrogenase |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0004361 | Molecular function | glutaryl-CoA dehydrogenase activity |
| GO_0000062 | Molecular function | fatty-acyl-CoA binding |
| GO_0050660 | Molecular function | flavin adenine dinucleotide binding |
| Gene name | GCDH |
| Protein name | Glutaryl CoA dehydrogenase Glutaryl-CoA dehydrogenase Glutaryl-CoA dehydrogenase, mitochondrial (EC 1.3.8.6) Glutaryl-CoA dehydrogenase, mitochondrial Mitochondrial glutaryl-Coenzyme A dehydrogenase Truncated glutaryl CoA dehydrogenase Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6) |
| Synonyms | |
| Description | FUNCTION: Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive. . |
| Accessions | ENST00000589039.5 ENST00000590472.5 A0A2H4FX81 A0A2H4G245 K7ER63 A0A2L2DH10 A0A2H4G235 A0A2L2DH18 G8FL39 A0A2H4G1S8 ENST00000222214.10 [Q92947-1] Q92947 K7ERX1 A0A1L3A5T2 A0A2H4FX52 ENST00000590445.5 K7ESA6 ENST00000591050.1 A0A2L2DH21 ENST00000588905.5 ENST00000590530.5 Q36741 A0A2L2DH19 A0A2H4FX70 A0A2L2DH25 A0A1L3A5U7 ENST00000591470.5 [Q92947-1] K7EKH1 K7EQ99 A0A2H4FX57 A0A2L2DH26 A0A2H4FWZ7 A0A2H4G0V0 K7ES74 K7EKT3 ENST00000587072.1 A0A2H4FX55 A0A2L2DH39 A0A1D6XXQ4 |
