Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 4 studies | 22% ± 9% |
Insufficient scRNA-seq data for expression of GCAT at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1199.97 | 2639 / 2642 | 100% | 42.07 | 704 / 705 |
prostate | 100% | 1644.92 | 245 / 245 | 99% | 101.23 | 499 / 502 |
skin | 100% | 768.90 | 1804 / 1809 | 98% | 52.38 | 464 / 472 |
thymus | 100% | 1203.74 | 653 / 653 | 98% | 32.75 | 590 / 605 |
bladder | 100% | 487.29 | 21 / 21 | 95% | 29.43 | 478 / 504 |
breast | 99% | 465.59 | 454 / 459 | 96% | 29.08 | 1068 / 1118 |
pancreas | 100% | 2776.87 | 328 / 328 | 94% | 19.41 | 168 / 178 |
liver | 100% | 1790.96 | 226 / 226 | 94% | 60.30 | 382 / 406 |
ovary | 98% | 616.30 | 177 / 180 | 93% | 24.04 | 402 / 430 |
intestine | 98% | 451.71 | 944 / 966 | 91% | 30.92 | 482 / 527 |
stomach | 100% | 656.02 | 359 / 359 | 88% | 24.08 | 251 / 286 |
uterus | 96% | 449.21 | 163 / 170 | 90% | 28.53 | 412 / 459 |
adrenal gland | 100% | 992.50 | 258 / 258 | 80% | 18.21 | 184 / 230 |
esophagus | 100% | 702.15 | 1441 / 1445 | 80% | 14.98 | 146 / 183 |
lung | 84% | 391.76 | 488 / 578 | 90% | 27.36 | 1042 / 1155 |
kidney | 100% | 697.39 | 89 / 89 | 73% | 15.46 | 658 / 901 |
eye | 0% | 0 | 0 / 0 | 100% | 59.52 | 80 / 80 |
ureter | 0% | 0 | 0 / 0 | 100% | 34.98 | 1 / 1 |
muscle | 99% | 669.00 | 795 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 1255.69 | 843 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 97% | 397.98 | 1289 / 1335 | 0% | 0 | 0 / 0 |
adipose | 96% | 401.61 | 1156 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 22.92 | 42 / 45 |
lymph node | 0% | 0 | 0 / 0 | 93% | 30.43 | 27 / 29 |
peripheral blood | 36% | 182.03 | 338 / 929 | 0% | 0 | 0 / 0 |
spleen | 14% | 28.00 | 33 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0009058 | Biological process | biosynthetic process |
GO_0006567 | Biological process | threonine catabolic process |
GO_0006520 | Biological process | amino acid metabolic process |
GO_0016607 | Cellular component | nuclear speck |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0005634 | Cellular component | nucleus |
GO_0008890 | Molecular function | glycine C-acetyltransferase activity |
GO_0030170 | Molecular function | pyridoxal phosphate binding |
Gene name | GCAT |
Protein name | Glycine C-acetyltransferase 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase) |
Synonyms | KBL |
Description | FUNCTION: Pyridoxal phosphate (PLP) dependent enzyme, which catalyzes the cleavage of 2-amino-3-oxobutanoate to glycine and acetyl-CoA. . |
Accessions | O75600 H7BZ75 ENST00000451984.1 C9IZC9 ENST00000445195.5 F2Z340 ENST00000426858.1 ENST00000248924.11 [O75600-1] ENST00000323205.10 [O75600-2] |