GBGT1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GBGT1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GBGT1 at tissue level.

III. Associated gene sets

GO_0005975Biological processcarbohydrate metabolic process
GO_0006486Biological processprotein glycosylation
GO_0030259Biological processlipid glycosylation
GO_0009247Biological processglycolipid biosynthetic process
GO_0000139Cellular componentGolgi membrane
GO_0005794Cellular componentGolgi apparatus
GO_0031982Cellular componentvesicle
GO_0047277Molecular functiongloboside alpha-N-acetylgalactosaminyltransferase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameGBGT1
Protein nameGloboside alpha-1,3-N-acetylgalactosaminyltransferase 1
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.-) (Forssman glycolipid synthase-like protein)
SynonymsUNQ2513/PRO6002
DescriptionFUNCTION: Has lost the ability to synthesize Forssman glycolipid antigen (FORS1/FG) . Might have acquired an alternative function in glycosphingolipid metabolism, but it remains to be established. It appears to have drifted more slowly than confirmed pseudogenes in the glycosyltransferase 6 family, suggesting that it has remained under evolutionary pressure. .

AccessionsQ5T7U8
ENST00000372043.7 [Q8N5D6-2]
J7Q261
ENST00000470431.5
J7PW20
J7Q2I4
ENST00000372038.7
ENST00000540636.6 [Q8N5D6-3]
A0A2R8Y4A7
ENST00000644196.1
ENST00000646215.1
ENST00000372036.4
A0A2R8YGC1
ENST00000372040.9 [Q8N5D6-1]
ENST00000487864.1
Q5T7V0
J7Q0Z1
Q8N5D6
J7Q1C6