GART report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006544Biological processglycine metabolic process
GO_0044208Biological process'de novo' AMP biosynthetic process
GO_0009168Biological processpurine ribonucleoside monophosphate biosynthetic process
GO_0097294Biological process'de novo' XMP biosynthetic process
GO_0006177Biological processGMP biosynthetic process
GO_0046654Biological processtetrahydrofolate biosynthetic process
GO_0003360Biological processbrainstem development
GO_0021549Biological processcerebellum development
GO_0006164Biological processpurine nucleotide biosynthetic process
GO_0021987Biological processcerebral cortex development
GO_0046084Biological processadenine biosynthetic process
GO_0006189Biological process'de novo' IMP biosynthetic process
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0004641Molecular functionphosphoribosylformylglycinamidine cyclo-ligase activity
GO_0004637Molecular functionphosphoribosylamine-glycine ligase activity
GO_0004644Molecular functionphosphoribosylglycinamide formyltransferase activity
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameGART
Protein nameTrifunctional purine biosynthetic protein adenosine-3
Glycinamide ribonucleotide formyltransferase
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)]
phosphoribosylglycinamide formyltransferase 1 (EC 2.1.2.2)
SynonymsPRGS
PGFT
DescriptionFUNCTION: Trifunctional enzyme that catalyzes three distinct reactions as part of the 'de novo' inosine monophosphate biosynthetic pathway. .

AccessionsENST00000573055.5
ENST00000430874.5
ENST00000381839.7 [P22102-1]
A0A140TA71
ENST00000361093.9 [P22102-2]
ENST00000366093.6
ENST00000438059.5
Q71VH3
ENST00000574289.5
ENST00000441403.1
H7C366
ENST00000575273.5
ENST00000571089.2
C9JTV6
ENST00000426819.5
C9JKQ7
ENST00000381831.7 [P22102-1]
P22102
ENST00000381815.9 [P22102-1]
F8WD69
Q3B7A7
C9JBJ1
C9JZG2
ENST00000424203.5