Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 6 studies | 30% ± 10% | |
endothelial cell | 4 studies | 21% ± 6% | |
astrocyte | 4 studies | 23% ± 8% | |
glutamatergic neuron | 3 studies | 39% ± 15% | |
dendritic cell | 3 studies | 21% ± 4% | |
abnormal cell | 3 studies | 22% ± 4% | |
basal cell | 3 studies | 25% ± 9% | |
transit amplifying cell | 3 studies | 33% ± 12% | |
interneuron | 3 studies | 35% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2773.14 | 1445 / 1445 | 100% | 39.95 | 183 / 183 |
ovary | 100% | 2357.38 | 180 / 180 | 100% | 33.86 | 430 / 430 |
stomach | 100% | 2358.06 | 359 / 359 | 100% | 39.61 | 286 / 286 |
lung | 100% | 2585.71 | 578 / 578 | 100% | 36.30 | 1154 / 1155 |
breast | 100% | 3241.28 | 459 / 459 | 100% | 40.44 | 1117 / 1118 |
intestine | 100% | 2639.57 | 966 / 966 | 100% | 42.39 | 526 / 527 |
uterus | 100% | 2468.26 | 170 / 170 | 100% | 41.05 | 458 / 459 |
bladder | 100% | 2886.43 | 21 / 21 | 100% | 38.86 | 502 / 504 |
prostate | 100% | 2232.07 | 245 / 245 | 99% | 24.14 | 498 / 502 |
skin | 100% | 4031.27 | 1809 / 1809 | 99% | 43.37 | 467 / 472 |
pancreas | 100% | 1912.27 | 328 / 328 | 99% | 25.04 | 176 / 178 |
thymus | 100% | 2360.04 | 653 / 653 | 99% | 20.88 | 598 / 605 |
brain | 99% | 1415.62 | 2607 / 2642 | 100% | 34.81 | 705 / 705 |
liver | 100% | 1776.24 | 226 / 226 | 95% | 16.24 | 387 / 406 |
kidney | 100% | 1951.93 | 89 / 89 | 95% | 17.29 | 852 / 901 |
adrenal gland | 100% | 2809.28 | 258 / 258 | 86% | 13.60 | 198 / 230 |
adipose | 100% | 3435.48 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 45.44 | 29 / 29 |
muscle | 100% | 2503.75 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2846.16 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 45.71 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.75 | 1 / 1 |
blood vessel | 100% | 2444.37 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 1769.03 | 826 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 28.78 | 75 / 80 |
peripheral blood | 81% | 2303.77 | 748 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006544 | Biological process | glycine metabolic process |
GO_0044208 | Biological process | 'de novo' AMP biosynthetic process |
GO_0009168 | Biological process | purine ribonucleoside monophosphate biosynthetic process |
GO_0097294 | Biological process | 'de novo' XMP biosynthetic process |
GO_0006177 | Biological process | GMP biosynthetic process |
GO_0046654 | Biological process | tetrahydrofolate biosynthetic process |
GO_0003360 | Biological process | brainstem development |
GO_0021549 | Biological process | cerebellum development |
GO_0006164 | Biological process | purine nucleotide biosynthetic process |
GO_0021987 | Biological process | cerebral cortex development |
GO_0046084 | Biological process | adenine biosynthetic process |
GO_0006189 | Biological process | 'de novo' IMP biosynthetic process |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005829 | Cellular component | cytosol |
GO_0004641 | Molecular function | phosphoribosylformylglycinamidine cyclo-ligase activity |
GO_0004637 | Molecular function | phosphoribosylamine-glycine ligase activity |
GO_0004644 | Molecular function | phosphoribosylglycinamide formyltransferase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | GART |
Protein name | Trifunctional purine biosynthetic protein adenosine-3 Glycinamide ribonucleotide formyltransferase Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] phosphoribosylglycinamide formyltransferase 1 (EC 2.1.2.2) |
Synonyms | PRGS PGFT |
Description | FUNCTION: Trifunctional enzyme that catalyzes three distinct reactions as part of the 'de novo' inosine monophosphate biosynthetic pathway. . |
Accessions | ENST00000573055.5 ENST00000430874.5 ENST00000381839.7 [P22102-1] A0A140TA71 ENST00000361093.9 [P22102-2] ENST00000366093.6 ENST00000438059.5 Q71VH3 ENST00000574289.5 ENST00000441403.1 H7C366 ENST00000575273.5 ENST00000571089.2 C9JTV6 ENST00000426819.5 C9JKQ7 ENST00000381831.7 [P22102-1] P22102 ENST00000381815.9 [P22102-1] F8WD69 Q3B7A7 C9JBJ1 C9JZG2 ENST00000424203.5 |