GAL3ST1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GAL3ST1 at tissue level.

III. Associated gene sets

GO_0006681Biological processgalactosylceramide metabolic process
GO_0046486Biological processglycerolipid metabolic process
GO_0006487Biological processprotein N-linked glycosylation
GO_0007283Biological processspermatogenesis
GO_0006688Biological processglycosphingolipid biosynthetic process
GO_0042552Biological processmyelination
GO_0006682Biological processgalactosylceramide biosynthetic process
GO_0006665Biological processsphingolipid metabolic process
GO_0000139Cellular componentGolgi membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0008146Molecular functionsulfotransferase activity
GO_0001733Molecular functiongalactosylceramide sulfotransferase activity

IV. Literature review

[source]
Gene nameGAL3ST1
Protein nameGalactose-3-O-sulfotransferase 1
Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase)
SynonymsCST
DescriptionFUNCTION: Catalyzes the transfer of a sulfate group to position 3 of non-reducing beta-galactosyl residues in glycerolipids and sphingolipids, therefore participates in the biosynthesis of sulfoglycolipids . Catalyzes the synthesis of galactosylceramide sulfate (sulfatide), a major lipid component of the myelin sheath and of monogalactosylalkylacylglycerol sulfate (seminolipid), present in spermatocytes . Seems to prefer beta-glycosides at the non-reducing termini of sugar chains attached to a lipid moiety . Also acts on lactosylceramide, galactosyl 1-alkyl-2-sn-glycerol and galactosyl diacylglycerol (in vitro) . .

AccessionsC9J2M1
ENST00000402321.5
Q99999
ENST00000401975.5
C9J4I2
C9JE31
C9JN55
C9JIS3
ENST00000406361.6
ENST00000426220.5
ENST00000431313.5
ENST00000411821.5
ENST00000427899.5
ENST00000441967.5
C9JU54
C9J993
ENST00000338911.6
ENST00000453479.1
ENST00000448604.1
C9JKD7
ENST00000423299.5
ENST00000402369.5
C9J2X7
C9JYD7
C9JTV3
C9J3S3
ENST00000437282.5
ENST00000406955.5
C9J6M2
ENST00000447224.5
C9K037
ENST00000452827.5
ENST00000428682.5
ENST00000423371.5
ENST00000443136.5
ENST00000416358.5
C9JGL4
ENST00000445645.5
C9JLB5