Insufficient scRNA-seq data for expression of GADL1 at single-cell level.
Insufficient scRNA-seq data for expression of GADL1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
muscle | 95% | 495.41 | 764 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 70% | 46.40 | 937 / 1335 | 0% | 0 | 0 / 0 |
esophagus | 62% | 203.37 | 890 / 1445 | 4% | 0.10 | 7 / 183 |
adrenal gland | 25% | 5.11 | 65 / 258 | 19% | 0.80 | 43 / 230 |
lung | 39% | 11.89 | 224 / 578 | 1% | 0.04 | 8 / 1155 |
ovary | 36% | 16.61 | 65 / 180 | 0% | 0.01 | 2 / 430 |
bladder | 33% | 9.14 | 7 / 21 | 0% | 0.04 | 2 / 504 |
kidney | 33% | 27.22 | 29 / 89 | 0% | 0.00 | 1 / 901 |
breast | 32% | 19.57 | 148 / 459 | 0% | 0.03 | 4 / 1118 |
adipose | 27% | 12.89 | 327 / 1204 | 0% | 0 | 0 / 0 |
prostate | 25% | 25.82 | 61 / 245 | 2% | 0.05 | 9 / 502 |
spleen | 15% | 3.00 | 36 / 241 | 0% | 0 | 0 / 0 |
uterus | 12% | 3.09 | 20 / 170 | 3% | 0.08 | 12 / 459 |
heart | 11% | 2.62 | 91 / 861 | 0% | 0 | 0 / 0 |
skin | 2% | 0.41 | 41 / 1809 | 7% | 0.29 | 32 / 472 |
brain | 5% | 3.19 | 139 / 2642 | 0% | 0.01 | 2 / 705 |
stomach | 3% | 1.58 | 12 / 359 | 1% | 0.02 | 3 / 286 |
intestine | 3% | 0.60 | 30 / 966 | 1% | 0.03 | 4 / 527 |
thymus | 2% | 0.55 | 16 / 653 | 0% | 0 | 0 / 605 |
liver | 1% | 0.14 | 2 / 226 | 0% | 0.01 | 2 / 406 |
eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
peripheral blood | 1% | 0.16 | 7 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
pancreas | 0% | 0 | 0 / 328 | 0% | 0 | 0 / 178 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0019752 | Biological process | carboxylic acid metabolic process |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0004068 | Molecular function | aspartate 1-decarboxylase activity |
GO_0030170 | Molecular function | pyridoxal phosphate binding |
GO_0004782 | Molecular function | sulfinoalanine decarboxylase activity |
GO_0016831 | Molecular function | carboxy-lyase activity |
Gene name | GADL1 |
Protein name | Acidic amino acid decarboxylase GADL1 (Aspartate 1-decarboxylase) (ADC) (HuADC) (EC 4.1.1.11) (Cysteine sulfinic acid decarboxylase) (CSADC) (HuCSADC) (EC 4.1.1.29) (Glutamate decarboxylase-like protein 1) |
Synonyms | |
Description | FUNCTION: May catalyze the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. Does not exhibit any decarboxylation activity toward glutamate. . |
Accessions | Q6ZQY3 ENST00000282538.10 [Q6ZQY3-1] ENST00000454381.3 [Q6ZQY3-3] |