Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| macrophage | 20 studies | 28% ± 8% | |
| classical monocyte | 11 studies | 26% ± 11% | |
| alveolar macrophage | 8 studies | 27% ± 6% | |
| non-classical monocyte | 7 studies | 27% ± 12% | |
| conventional dendritic cell | 5 studies | 24% ± 6% | |
| myeloid cell | 5 studies | 27% ± 7% | |
| monocyte | 5 studies | 21% ± 5% | |
| microglial cell | 5 studies | 24% ± 5% | |
| epithelial cell | 4 studies | 29% ± 14% | |
| dendritic cell | 4 studies | 34% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 23% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 6405.28 | 653 / 653 | 100% | 103.76 | 604 / 605 |
| liver | 100% | 4410.32 | 226 / 226 | 100% | 103.24 | 404 / 406 |
| prostate | 100% | 6492.84 | 245 / 245 | 99% | 164.14 | 499 / 502 |
| kidney | 100% | 6028.07 | 89 / 89 | 99% | 129.18 | 895 / 901 |
| breast | 100% | 5750.27 | 459 / 459 | 99% | 116.22 | 1107 / 1118 |
| skin | 100% | 4707.92 | 1806 / 1809 | 99% | 114.27 | 466 / 472 |
| brain | 99% | 3292.96 | 2605 / 2642 | 100% | 84.73 | 704 / 705 |
| pancreas | 100% | 3292.60 | 328 / 328 | 98% | 78.02 | 175 / 178 |
| adrenal gland | 100% | 5264.04 | 258 / 258 | 97% | 77.36 | 224 / 230 |
| lung | 100% | 8242.95 | 578 / 578 | 97% | 114.26 | 1118 / 1155 |
| uterus | 100% | 5203.76 | 170 / 170 | 97% | 94.65 | 444 / 459 |
| ovary | 99% | 3205.75 | 178 / 180 | 97% | 73.10 | 415 / 430 |
| bladder | 100% | 5411.05 | 21 / 21 | 93% | 94.14 | 471 / 504 |
| esophagus | 99% | 3957.18 | 1436 / 1445 | 90% | 78.16 | 164 / 183 |
| stomach | 100% | 3753.19 | 358 / 359 | 88% | 57.87 | 251 / 286 |
| intestine | 100% | 4953.95 | 966 / 966 | 84% | 47.75 | 442 / 527 |
| adipose | 100% | 5347.87 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 117.78 | 80 / 80 |
| spleen | 100% | 9873.93 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 95.57 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 35.22 | 1 / 1 |
| muscle | 100% | 4435.84 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 4850.49 | 1328 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 3828.57 | 849 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 62.84 | 28 / 29 |
| peripheral blood | 96% | 5759.51 | 892 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0000023 | Biological process | maltose metabolic process |
| GO_0007040 | Biological process | lysosome organization |
| GO_0035904 | Biological process | aorta development |
| GO_0009888 | Biological process | tissue development |
| GO_0046716 | Biological process | muscle cell cellular homeostasis |
| GO_0002086 | Biological process | diaphragm contraction |
| GO_0005980 | Biological process | glycogen catabolic process |
| GO_0050885 | Biological process | neuromuscular process controlling balance |
| GO_0002026 | Biological process | regulation of the force of heart contraction |
| GO_0060048 | Biological process | cardiac muscle contraction |
| GO_0050884 | Biological process | neuromuscular process controlling posture |
| GO_0005985 | Biological process | sucrose metabolic process |
| GO_0043181 | Biological process | vacuolar sequestering |
| GO_0007626 | Biological process | locomotory behavior |
| GO_0061723 | Biological process | glycophagy |
| GO_0006006 | Biological process | glucose metabolic process |
| GO_0003007 | Biological process | heart morphogenesis |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005764 | Cellular component | lysosome |
| GO_0035577 | Cellular component | azurophil granule membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0070821 | Cellular component | tertiary granule membrane |
| GO_0101003 | Cellular component | ficolin-1-rich granule membrane |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0043202 | Cellular component | lysosomal lumen |
| GO_0120282 | Cellular component | autolysosome lumen |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0030246 | Molecular function | carbohydrate binding |
| GO_0004558 | Molecular function | alpha-1,4-glucosidase activity |
| GO_0090599 | Molecular function | alpha-glucosidase activity |
| GO_0032450 | Molecular function | maltose alpha-glucosidase activity |
| Gene name | GAA |
| Protein name | Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) alpha-glucosidase (EC 3.2.1.20) Alpha glucosidase Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase] |
| Synonyms | |
| Description | FUNCTION: Essential for the degradation of glycogen in lysosomes . Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans . . |
| Accessions | ENST00000577106.5 ENST00000570803.6 ENST00000302262.8 ENST00000390015.7 P10253 ENST00000707779.1 ENST00000707781.1 ENST00000572080.2 I3L3L3 ENST00000570803.5 ENST00000577106.6 I3L0S5 I3L2V9 |
