Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| Mueller cell | 5 studies | 25% ± 6% | |
| type B pancreatic cell | 3 studies | 54% ± 20% |
Insufficient scRNA-seq data for expression of G6PC2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 1231.60 | 328 / 328 | 67% | 26.73 | 119 / 178 |
| stomach | 68% | 12.72 | 245 / 359 | 1% | 0.01 | 2 / 286 |
| brain | 49% | 5.69 | 1283 / 2642 | 18% | 0.74 | 124 / 705 |
| breast | 64% | 14.09 | 293 / 459 | 1% | 0.02 | 8 / 1118 |
| intestine | 59% | 6.49 | 570 / 966 | 2% | 1.90 | 10 / 527 |
| lung | 60% | 16.09 | 349 / 578 | 0% | 0.01 | 3 / 1155 |
| prostate | 51% | 5.82 | 125 / 245 | 0% | 0 | 0 / 502 |
| kidney | 48% | 7.04 | 43 / 89 | 2% | 0.03 | 16 / 901 |
| adipose | 50% | 7.17 | 598 / 1204 | 0% | 0 | 0 / 0 |
| skin | 41% | 7.31 | 741 / 1809 | 6% | 0.17 | 30 / 472 |
| ovary | 44% | 4.26 | 80 / 180 | 0% | 0 | 0 / 430 |
| liver | 41% | 3.13 | 92 / 226 | 0% | 0.07 | 1 / 406 |
| uterus | 40% | 4.84 | 68 / 170 | 0% | 0 | 0 / 459 |
| adrenal gland | 39% | 4.43 | 101 / 258 | 0% | 0.04 | 1 / 230 |
| thymus | 35% | 3.71 | 231 / 653 | 0% | 0 | 0 / 605 |
| heart | 31% | 2.65 | 264 / 861 | 0% | 0 | 0 / 0 |
| spleen | 29% | 2.80 | 69 / 241 | 0% | 0 | 0 / 0 |
| esophagus | 26% | 2.03 | 373 / 1445 | 1% | 0.01 | 1 / 183 |
| muscle | 20% | 1.19 | 157 / 803 | 0% | 0 | 0 / 0 |
| bladder | 19% | 3.52 | 4 / 21 | 0% | 0 | 0 / 504 |
| blood vessel | 14% | 1.08 | 185 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.11 | 2 / 80 |
| peripheral blood | 2% | 0.10 | 21 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0050796 | Biological process | regulation of insulin secretion |
| GO_0051156 | Biological process | glucose 6-phosphate metabolic process |
| GO_0006094 | Biological process | gluconeogenesis |
| GO_0042593 | Biological process | glucose homeostasis |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0004346 | Molecular function | glucose-6-phosphatase activity |
| Gene name | G6PC2 |
| Protein name | Glucose-6-phosphatase 2 (Glucose-6-phosphatase catalytic subunit 2) Glucose-6-phosphatase 2 (G-6-Pase 2) (G6Pase 2) (EC 3.1.3.9) (Islet-specific glucose-6-phosphatase catalytic subunit-related protein) |
| Synonyms | IGRP |
| Description | FUNCTION: May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis (By similarity). . |
| Accessions | ENST00000622133.4 [Q9NQR9-1] ENST00000282075.5 [Q9NQR9-2] ENST00000612807.1 [Q9NQR9-3] ENST00000618310.1 Q9NQR9 ENST00000421979.1 C9IYU7 ENST00000617403.1 [Q9NQR9-2] ENST00000429379.2 [Q9NQR9-3] ENST00000375363.8 [Q9NQR9-1] |