FUT5 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of FUT5 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	96%	11.81	216 / 226	1%	0.01	3 / 406
brain	68%	4.50	1800 / 2642	0%	0	0 / 705
skin	66%	9.40	1201 / 1809	0%	0	0 / 472
esophagus	65%	7.60	933 / 1445	0%	0	0 / 183
intestine	64%	5.77	614 / 966	0%	0.00	1 / 527
prostate	58%	2.76	141 / 245	0%	0	0 / 502
kidney	54%	3.21	48 / 89	0%	0	0 / 901
breast	48%	2.92	222 / 459	0%	0.00	1 / 1118
bladder	48%	2.05	10 / 21	0%	0	0 / 504
lung	44%	2.37	257 / 578	0%	0.00	1 / 1155
adipose	42%	3.32	507 / 1204	0%	0	0 / 0
stomach	39%	2.26	140 / 359	0%	0	0 / 286
spleen	39%	1.44	93 / 241	0%	0	0 / 0
peripheral blood	38%	2.06	355 / 929	0%	0	0 / 0
uterus	35%	1.35	59 / 170	1%	0.04	5 / 459
pancreas	35%	1.12	116 / 328	0%	0	0 / 178
blood vessel	33%	1.52	437 / 1335	0%	0	0 / 0
ovary	28%	1.54	50 / 180	0%	0.01	1 / 430
heart	27%	0.92	229 / 861	0%	0	0 / 0
thymus	19%	0.54	127 / 653	0%	0	0 / 605
muscle	16%	0.82	132 / 803	0%	0	0 / 0
adrenal gland	12%	0.37	32 / 258	0%	0	0 / 230
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0005975	Biological process	carbohydrate metabolic process
GO_0006672	Biological process	ceramide metabolic process
GO_0006487	Biological process	protein N-linked glycosylation
GO_0009312	Biological process	oligosaccharide biosynthetic process
GO_0006493	Biological process	protein O-linked glycosylation
GO_0042355	Biological process	L-fucose catabolic process
GO_0009311	Biological process	oligosaccharide metabolic process
GO_0006486	Biological process	protein glycosylation
GO_0036065	Biological process	fucosylation
GO_0000139	Cellular component	Golgi membrane
GO_0032580	Cellular component	Golgi cisterna membrane
GO_0005794	Cellular component	Golgi apparatus
GO_0017060	Molecular function	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity
GO_0046920	Molecular function	alpha-(1->3)-fucosyltransferase activity
GO_0008417	Molecular function	fucosyltransferase activity
GO_0017083	Molecular function	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity

Gene name	FUT5
Protein name	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase)
Synonyms
Description	FUNCTION: Catalyzes preferentially the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl-beta-D-glucosamine (GlcNAc) of an N-acetyllactosamine unit (type 2 chain) of an oligosaccharide, or a glycoprotein- and a glycolipid-linked N-acetyllactosamine unit via an alpha (1,3) linkage and participates in the surface expression of VIM-2, Lewis X/SSEA-1 and sialyl Lewis X antigens . Preferentially transfers fucose to the GlcNAc of an internal N-acetyllactosamine unit of a poly-N-acetyllactosamine chain acceptor substrate . Also catalyzes to a lesser extend the transfer of L-fucose to the GlcNAc of a type 1 (beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl) or H-type 1 (alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-D-GlcNAc) chain oligosaccharide via an alpha (1,4) linkage . Preferentially catalyzes sialylated type 2 oligosaccharide acceptors over neutral type 2 or H type 2 (alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-D-GlcNAc) oligosaccharide acceptors . Lactose-based structures are also acceptor substrates . .
Accessions	ENST00000588525.1 Q11128 ENST00000252675.6

FUT5 report