FUOM report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006004Biological processfucose metabolic process
GO_0036065Biological processfucosylation
GO_0005829Cellular componentcytosol
GO_0042806Molecular functionfucose binding
GO_0036373Molecular functionL-fucose mutarotase activity
GO_0016857Molecular functionracemase and epimerase activity, acting on carbohydrates and derivatives

IV. Literature review

[source]
Gene nameFUOM
Protein nameL-fucose mutarotase (EC 5.1.3.29)
Fucose mutarotase (EC 5.1.3.29)
SynonymsC10orf125
DescriptionFUNCTION: Involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes. .

AccessionsENST00000278025.9 [A2VDF0-1]
A2VDF0
X6R6T9
X6RK00
ENST00000368552.7 [A2VDF0-2]
ENST00000368551.1
ENST00000447176.5