Name | Number of supported studies | Average coverage | |
---|---|---|---|
cardiac muscle cell | 4 studies | 23% ± 5% | |
erythroblast | 3 studies | 20% ± 4% | |
epithelial cell | 3 studies | 30% ± 11% | |
astrocyte | 3 studies | 22% ± 4% | |
erythrocyte | 3 studies | 37% ± 14% | |
oligodendrocyte | 3 studies | 26% ± 3% | |
epithelial cell of proximal tubule | 3 studies | 24% ± 12% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 3 studies | 29% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 2940.14 | 2642 / 2642 | 100% | 44.69 | 702 / 705 |
liver | 100% | 1752.16 | 225 / 226 | 100% | 57.90 | 404 / 406 |
adrenal gland | 100% | 3239.37 | 258 / 258 | 99% | 46.60 | 227 / 230 |
prostate | 98% | 1056.54 | 241 / 245 | 99% | 35.75 | 499 / 502 |
kidney | 100% | 2942.82 | 89 / 89 | 97% | 36.90 | 877 / 901 |
ovary | 100% | 1888.19 | 180 / 180 | 97% | 24.92 | 417 / 430 |
pancreas | 100% | 855.64 | 327 / 328 | 97% | 14.93 | 172 / 178 |
thymus | 99% | 903.82 | 645 / 653 | 96% | 21.97 | 580 / 605 |
intestine | 99% | 1075.90 | 952 / 966 | 96% | 22.92 | 505 / 527 |
stomach | 100% | 1064.18 | 358 / 359 | 94% | 25.57 | 270 / 286 |
breast | 97% | 698.49 | 444 / 459 | 95% | 22.99 | 1060 / 1118 |
bladder | 95% | 726.29 | 20 / 21 | 88% | 18.25 | 445 / 504 |
uterus | 99% | 848.02 | 168 / 170 | 79% | 15.38 | 362 / 459 |
lung | 90% | 630.20 | 519 / 578 | 86% | 18.10 | 988 / 1155 |
skin | 59% | 283.56 | 1070 / 1809 | 96% | 40.86 | 452 / 472 |
esophagus | 79% | 678.24 | 1146 / 1445 | 74% | 15.09 | 136 / 183 |
eye | 0% | 0 | 0 / 0 | 100% | 109.42 | 80 / 80 |
ureter | 0% | 0 | 0 / 0 | 100% | 24.57 | 1 / 1 |
blood vessel | 98% | 910.49 | 1313 / 1335 | 0% | 0 | 0 / 0 |
heart | 95% | 1906.59 | 820 / 861 | 0% | 0 | 0 / 0 |
adipose | 93% | 611.97 | 1123 / 1204 | 0% | 0 | 0 / 0 |
muscle | 90% | 910.34 | 721 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 44% | 4.78 | 20 / 45 |
spleen | 43% | 162.53 | 103 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 7% | 32.70 | 63 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030389 | Biological process | fructosamine metabolic process |
GO_0036525 | Biological process | protein deglycation |
GO_0030393 | Biological process | fructoselysine metabolic process |
GO_0043687 | Biological process | post-translational protein modification |
GO_0030855 | Biological process | epithelial cell differentiation |
GO_0005575 | Cellular component | cellular_component |
GO_0005829 | Cellular component | cytosol |
GO_0102193 | Molecular function | protein-ribulosamine 3-kinase activity |
GO_0102194 | Molecular function | protein-fructosamine 3-kinase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0016301 | Molecular function | kinase activity |
Gene name | FN3K |
Protein name | Fructosamine-3-kinase (EC 2.7.1.171) (Protein-psicosamine 3-kinase FN3K) (Protein-ribulosamine 3-kinase FN3K) (EC 2.7.1.172) |
Synonyms | |
Description | FUNCTION: Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate . Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions . Involved in intracellular deglycation in erythrocytes . Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function (By similarity). Also able to phosphorylate psicosamines and ribulosamines . . |
Accessions | ENST00000300784.8 Q9H479 |