FLG2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of FLG2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	87%	114981.57	1581 / 1809	10%	5.97	45 / 472
esophagus	78%	82.60	1132 / 1445	8%	0.35	15 / 183
heart	79%	55.83	676 / 861	0%	0	0 / 0
blood vessel	78%	100.11	1047 / 1335	0%	0	0 / 0
adipose	77%	124.23	929 / 1204	0%	0	0 / 0
breast	76%	49.37	349 / 459	1%	0.12	8 / 1118
ovary	76%	47.06	137 / 180	0%	0	0 / 430
muscle	72%	88.58	579 / 803	0%	0	0 / 0
uterus	68%	41.06	116 / 170	2%	0.08	10 / 459
thymus	67%	46.40	438 / 653	0%	0	0 / 605
pancreas	66%	44.53	217 / 328	0%	0	0 / 178
stomach	65%	40.88	232 / 359	1%	0.01	2 / 286
lung	58%	62.17	337 / 578	1%	0.03	13 / 1155
intestine	58%	41.65	562 / 966	1%	0.04	4 / 527
prostate	56%	27.56	136 / 245	0%	0.01	2 / 502
adrenal gland	53%	31.83	138 / 258	0%	0	0 / 230
peripheral blood	45%	26.34	416 / 929	0%	0	0 / 0
liver	41%	35.49	93 / 226	0%	0	0 / 406
brain	40%	26.47	1047 / 2642	0%	0	0 / 705
spleen	39%	21.23	95 / 241	0%	0	0 / 0
kidney	30%	16.92	27 / 89	0%	0.00	2 / 901
bladder	29%	9.71	6 / 21	1%	0.10	7 / 504
tonsil	0%	0	0 / 0	2%	0.03	1 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0048730	Biological process	epidermis morphogenesis
GO_0007155	Biological process	cell adhesion
GO_0061436	Biological process	establishment of skin barrier
GO_0001533	Cellular component	cornified envelope
GO_1904724	Cellular component	tertiary granule lumen
GO_0005737	Cellular component	cytoplasm
GO_0036457	Cellular component	keratohyalin granule
GO_0005576	Cellular component	extracellular region
GO_0005634	Cellular component	nucleus
GO_0005509	Molecular function	calcium ion binding
GO_0046914	Molecular function	transition metal ion binding
GO_0005198	Molecular function	structural molecule activity

Gene name	FLG2
Protein name	Alternative protein FLG2 Filaggrin-2 (FLG-2) (Intermediate filament-associated and psoriasis-susceptibility protein) (Ifapsoriasin)
Synonyms	IFPS
Description	FUNCTION: Essential for normal cell-cell adhesion in the cornified cell layers . Important for proper integrity and mechanical strength of the stratum corneum of the epidermis . .
Accessions	L8E7D3 ENST00000388718.5 Q5D862

FLG2 report