FCAR | OmnibusX

Name	Number of supported studies	Average coverage
classical monocyte	7 studies	21% ± 5%	Explore

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FCAR at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	99%	706.90	575 / 578	20%	0.51	231 / 1155
spleen	100%	1031.50	240 / 241	0%	0	0 / 0
peripheral blood	82%	7813.29	764 / 929	0%	0	0 / 0
adipose	77%	175.39	922 / 1204	0%	0	0 / 0
liver	54%	60.94	121 / 226	2%	0.03	8 / 406
stomach	28%	41.91	100 / 359	18%	0.51	52 / 286
breast	41%	40.05	190 / 459	2%	0.04	25 / 1118
heart	44%	49.34	375 / 861	0%	0	0 / 0
kidney	34%	28.22	30 / 89	6%	0.13	52 / 901
intestine	26%	26.66	251 / 966	13%	0.38	68 / 527
bladder	29%	34.33	6 / 21	9%	0.28	47 / 504
brain	16%	10.86	429 / 2642	21%	0.52	145 / 705
thymus	34%	26.75	223 / 653	0%	0.01	3 / 605
ovary	23%	13.69	41 / 180	11%	0.18	47 / 430
blood vessel	34%	39.87	450 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	28%	1.18	8 / 29
esophagus	17%	15.01	245 / 1445	9%	0.21	16 / 183
adrenal gland	22%	12.16	58 / 258	2%	0.06	5 / 230
uterus	21%	22.41	36 / 170	3%	0.31	15 / 459
prostate	17%	14.65	42 / 245	0%	0.01	2 / 502
pancreas	6%	3.41	19 / 328	8%	0.12	14 / 178
muscle	12%	6.19	96 / 803	0%	0	0 / 0
skin	4%	2.41	66 / 1809	4%	0.06	18 / 472
tonsil	0%	0	0 / 0	4%	0.07	2 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

IV. Literature review

[source]

Gene name	FCAR
Protein name	Immunoglobulin alpha Fc receptor FCAR variant 14 Immunoglobulin alpha Fc receptor (IgA Fc receptor) (CD antigen CD89) FCAR
Synonyms	CD89
Description	FUNCTION: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. .
Accessions	ENST00000612159.4 [P24071-9] A0A0G2JPZ0 A5Y2F0 ENST00000619822.4 [P24071-2] ENST00000353758.8 [P24071-7] A0A0G2JM28 ENST00000614917.4 [P24071-2] ENST00000613318.4 [P24071-4] ENST00000620873.4 [P24071-11] ENST00000638285.1 [P24071-8] A0A0G2JM53 ENST00000621702.4 [P24071-1] ENST00000612836.4 ENST00000612918.4 [P24071-3] ENST00000622737.4 [P24071-1] ENST00000612803.4 [P24071-8] ENST00000618985.4 [P24071-5] A0A1P8A760 ENST00000612150.4 [P24071-3] ENST00000614893.4 [P24071-2] ENST00000622646.1 [P24071-7] ENST00000618149.4 ENST00000622883.4 [P24071-4] ENST00000611018.4 [P24071-11] ENST00000640582.2 [P24071-1] ENST00000622491.4 [P24071-8] ENST00000612815.4 [P24071-8] ENST00000621289.4 [P24071-5] ENST00000616969.4 [P24071-5] A0A0G2JNS3 ENST00000616340.4 [P24071-10] ENST00000615192.1 ENST00000615800.4 [P24071-4] ENST00000620270.4 [P24071-11] ENST00000613298.4 [P24071-9] A0A0G2JPP7 ENST00000391724.3 [P24071-11] A0A0G2JM27 ENST00000621417.4 [P24071-5] ENST00000359272.8 [P24071-10] ENST00000615937.4 [P24071-11] ENST00000617778.4 [P24071-3] ENST00000622470.1 [P24071-7] ENST00000610340.4 [P24071-8] P24071 ENST00000622157.4 [P24071-1] ENST00000345937.8 [P24071-3] ENST00000616878.4 [P24071-9] ENST00000614689.4 [P24071-5] ENST00000621684.4 [P24071-3] ENST00000617762.4 [P24071-5] ENST00000618287.4 [P24071-10] ENST00000618328.4 [P24071-10] ENST00000618805.4 [P24071-2] ENST00000617025.4 [P24071-3] ENST00000617696.4 [P24071-9] ENST00000614954.4 [P24071-9] ENST00000619073.4 [P24071-8] ENST00000620179.1 [P24071-7] ENST00000620397.4 [P24071-5] ENST00000488066.5 [P24071-5] A0A0G2JP11 A5Y2E9 ENST00000613685.4 [P24071-11] ENST00000622904.4 [P24071-11] ENST00000614433.4 [P24071-2] ENST00000617964.1 [P24071-7] ENST00000611871.4 [P24071-10] ENST00000613201.4 [P24071-4] ENST00000617766.4 [P24071-4] ENST00000391723.7 [P24071-8] ENST00000619385.4 [P24071-1] ENST00000620801.4 [P24071-1] ENST00000622777.4 [P24071-10] ENST00000391725.7 [P24071-2] ENST00000355524.8 [P24071-1] ENST00000620162.4 [P24071-11] ENST00000615110.4 [P24071-2] ENST00000640584.1 [P24071-5] ENST00000613199.4 [P24071-1] ENST00000638206.1 [P24071-3] ENST00000639455.1 [P24071-9] ENST00000613663.4 [P24071-4] ENST00000619155.4 [P24071-5] ENST00000618658.4 [P24071-4] ENST00000638453.1 [P24071-4] A0A0G2JLU6 ENST00000639428.1 [P24071-11] ENST00000611130.4 [P24071-11] ENST00000615703.4 [P24071-4] ENST00000614298.4 [P24071-9] ENST00000621009.4 [P24071-3] ENST00000622543.4 [P24071-3] ENST00000621755.1 [P24071-7] ENST00000619414.4 [P24071-2] ENST00000618271.1 [P24071-7] ENST00000615040.4 [P24071-10] ENST00000622014.4 ENST00000639178.1 [P24071-2] ENST00000469767.5 [P24071-4] ENST00000614052.4 ENST00000639223.1 [P24071-10] ENST00000622349.4 A0A0G2JPZ4 ENST00000614226.4 [P24071-1] ENST00000620822.1 [P24071-7] ENST00000391726.7 [P24071-9] ENST00000619953.4 ENST00000620561.4 ENST00000615888.4 ENST00000640070.2 ENST00000640025.2 [P24071-1] ENST00000615719.1 [P24071-7] ENST00000611409.4 ENST00000621004.4 [P24071-10] ENST00000615361.4 [P24071-9] ENST00000612505.4 [P24071-8] ENST00000610397.4 [P24071-3] ENST00000639163.1 [P24071-7] ENST00000615829.4 [P24071-1] A0A0G2JNH4 ENST00000621882.1 [P24071-7] ENST00000638212.2 [P24071-1] ENST00000638906.2 ENST00000617610.4 ENST00000617609.4 [P24071-10] ENST00000611943.4 [P24071-2] ENST00000610786.4 [P24071-8]

GO_0006955	Biological process	immune response
GO_0002764	Biological process	immune response-regulating signaling pathway
GO_0070821	Cellular component	tertiary granule membrane
GO_0005576	Cellular component	extracellular region
GO_0035579	Cellular component	specific granule membrane
GO_0005886	Cellular component	plasma membrane
GO_0101003	Cellular component	ficolin-1-rich granule membrane
GO_0019862	Molecular function	IgA binding

FCAR report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review