FBXW12 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FBXW12 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FBXW12 at tissue level.

III. Associated gene sets

GO_0016567Biological processprotein ubiquitination
GO_0005829Cellular componentcytosol

IV. Literature review

[source]
Gene nameFBXW12
Protein nameFBXW12 protein
F-box and WD repeat domain containing 12
F-box/WD repeat-containing protein 12 (F-box and WD-40 domain-containing protein 12) (F-box only protein 35)
SynonymsFBXO35
FBW12
FBXO12
DescriptionFUNCTION: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex . Promotes degradation of interleukin-22 receptor subunit IL22RA1 in resting and IL22-stimulated conditions by facilitating its ubiquitination . Functions as a cell growth suppressor . .

AccessionsA4FU26
ENST00000436231.5
ENST00000296438.9 [Q6X9E4-1]
ENST00000445170.5 [Q6X9E4-3]
Q6X9E4
C9JK86
ENST00000415155.5 [Q6X9E4-2]
Q494Z1