Insufficient scRNA-seq data for expression of FBXW10 at single-cell level.
Insufficient scRNA-seq data for expression of FBXW10 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 95% | 65.00 | 214 / 226 | 17% | 0.70 | 70 / 406 |
adrenal gland | 100% | 73.03 | 257 / 258 | 7% | 0.17 | 16 / 230 |
thymus | 100% | 126.13 | 652 / 653 | 1% | 0.03 | 8 / 605 |
muscle | 92% | 52.20 | 737 / 803 | 0% | 0 | 0 / 0 |
brain | 83% | 49.66 | 2199 / 2642 | 5% | 0.09 | 38 / 705 |
kidney | 83% | 26.47 | 74 / 89 | 1% | 0.02 | 8 / 901 |
bladder | 81% | 17.52 | 17 / 21 | 2% | 0.04 | 9 / 504 |
prostate | 81% | 19.39 | 198 / 245 | 0% | 0.00 | 1 / 502 |
stomach | 77% | 19.08 | 277 / 359 | 2% | 0.04 | 7 / 286 |
lung | 68% | 42.25 | 392 / 578 | 5% | 0.10 | 55 / 1155 |
esophagus | 61% | 15.18 | 880 / 1445 | 8% | 0.16 | 15 / 183 |
breast | 62% | 12.61 | 283 / 459 | 3% | 0.05 | 28 / 1118 |
ovary | 59% | 9.92 | 107 / 180 | 0% | 0 | 0 / 430 |
adipose | 58% | 16.52 | 704 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 51% | 8.94 | 684 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 48% | 7.09 | 157 / 328 | 0% | 0 | 0 / 178 |
intestine | 47% | 8.72 | 455 / 966 | 1% | 0.01 | 4 / 527 |
uterus | 40% | 11.66 | 68 / 170 | 2% | 0.04 | 10 / 459 |
skin | 34% | 6.57 | 620 / 1809 | 0% | 0.03 | 1 / 472 |
spleen | 27% | 4.05 | 66 / 241 | 0% | 0 | 0 / 0 |
heart | 25% | 3.45 | 215 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 0.19 | 10 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0005829 | Cellular component | cytosol |
Gene name | FBXW10 |
Protein name | F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10) (Ubiquitin ligase-specificity factor) F-box and WD repeat domain containing 10 |
Synonyms | |
Description | FUNCTION: Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1. . |
Accessions | ENST00000574478.1 ENST00000301938.4 [Q5XX13-3] ENST00000308799.8 [Q5XX13-2] Q5XX13 ENST00000395665.9 [Q5XX13-1] J3QLH9 |