Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 7 studies | 21% ± 5% | |
| epithelial cell | 3 studies | 19% ± 3% | |
| capillary endothelial cell | 3 studies | 18% ± 2% | |
| GABAergic neuron | 3 studies | 25% ± 2% | |
| glutamatergic neuron | 3 studies | 22% ± 3% | |
| fibroblast | 3 studies | 19% ± 1% | |
| smooth muscle cell | 3 studies | 23% ± 7% |
Insufficient scRNA-seq data for expression of EOGT at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 4415.98 | 578 / 578 | 100% | 16.71 | 1152 / 1155 |
| bladder | 100% | 3562.43 | 21 / 21 | 100% | 16.77 | 502 / 504 |
| esophagus | 100% | 3728.87 | 1439 / 1445 | 100% | 21.59 | 183 / 183 |
| prostate | 100% | 4124.01 | 245 / 245 | 99% | 15.41 | 499 / 502 |
| breast | 100% | 3002.81 | 459 / 459 | 99% | 14.83 | 1110 / 1118 |
| thymus | 99% | 1281.51 | 647 / 653 | 100% | 12.17 | 602 / 605 |
| uterus | 100% | 4012.88 | 170 / 170 | 98% | 18.77 | 451 / 459 |
| intestine | 99% | 2552.97 | 961 / 966 | 98% | 11.82 | 517 / 527 |
| stomach | 96% | 1909.01 | 344 / 359 | 99% | 15.08 | 283 / 286 |
| adrenal gland | 99% | 1243.88 | 255 / 258 | 94% | 13.07 | 217 / 230 |
| skin | 98% | 1779.29 | 1777 / 1809 | 94% | 16.38 | 444 / 472 |
| pancreas | 90% | 991.02 | 296 / 328 | 98% | 15.61 | 174 / 178 |
| ovary | 98% | 1723.54 | 177 / 180 | 76% | 4.78 | 328 / 430 |
| brain | 78% | 702.35 | 2061 / 2642 | 95% | 6.95 | 671 / 705 |
| kidney | 74% | 781.44 | 66 / 89 | 94% | 12.93 | 846 / 901 |
| adipose | 100% | 2563.63 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 6603.73 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 16.49 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 10.85 | 1 / 1 |
| spleen | 99% | 1380.58 | 239 / 241 | 0% | 0 | 0 / 0 |
| muscle | 99% | 1749.22 | 794 / 803 | 0% | 0 | 0 / 0 |
| heart | 95% | 2208.38 | 819 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 11.26 | 27 / 29 |
| liver | 25% | 189.58 | 56 / 226 | 65% | 4.30 | 262 / 406 |
| eye | 0% | 0 | 0 / 0 | 36% | 2.02 | 29 / 80 |
| peripheral blood | 16% | 137.19 | 152 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006493 | Biological process | protein O-linked glycosylation |
| GO_0097370 | Biological process | protein O-GlcNAcylation via threonine |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0097363 | Molecular function | protein O-acetylglucosaminyltransferase activity |
| Gene name | EOGT |
| Protein name | EGF domain specific O-linked N-acetylglucosamine transferase EGF domain-specific O-linked N-acetylglucosamine transferase (EC 2.4.1.255) (Extracellular O-linked N-acetylglucosamine transferase) C3orf64 protein (EGF domain specific O-linked N-acetylglucosamine transferase) |
| Synonyms | AER61 C3orf64 EOGT1 |
| Description | FUNCTION: Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains. . |
| Accessions | F5H225 Q5NDL2 ENST00000403140.6 ENST00000540955.5 [Q5NDL2-3] Q8N329 ENST00000456376.2 ENST00000615922.1 C9J4G5 ENST00000295571.9 [Q5NDL2-3] C9JQM7 ENST00000540764.5 [Q5NDL2-1] ENST00000383701.8 [Q5NDL2-1] ENST00000424374.5 |
