ENTPD8 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ENTPD8 at tissue level.

III. Associated gene sets

GO_0009134Biological processnucleoside diphosphate catabolic process
GO_0009124Biological processnucleoside monophosphate biosynthetic process
GO_0009133Biological processnucleoside diphosphate biosynthetic process
GO_0005886Cellular componentplasma membrane
GO_0004382Molecular functionGDP phosphatase activity
GO_0045134Molecular functionUDP phosphatase activity
GO_0004050Molecular functionapyrase activity
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding
GO_0017111Molecular functionribonucleoside triphosphate phosphatase activity

IV. Literature review

[source]
Gene nameENTPD8
Protein nameEctonucleoside triphosphate diphosphohydrolase 8 (EC 3.6.1.5)
Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5)
SynonymsUNQ2492/PRO5779
DescriptionFUNCTION: Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP. .

AccessionsENST00000344119.6 [Q5MY95-2]
H7C5J8
ENST00000371506.7 [Q5MY95-1]
Q5MY95
ENST00000493135.1