Name | Number of supported studies | Average coverage | |
---|---|---|---|
goblet cell | 6 studies | 28% ± 9% | |
enterocyte | 3 studies | 17% ± 2% |
Insufficient scRNA-seq data for expression of ENTPD8 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 796.35 | 226 / 226 | 83% | 10.32 | 335 / 406 |
pancreas | 100% | 155.43 | 328 / 328 | 78% | 12.33 | 139 / 178 |
stomach | 79% | 421.34 | 283 / 359 | 76% | 18.18 | 218 / 286 |
thymus | 89% | 70.56 | 581 / 653 | 66% | 4.17 | 398 / 605 |
intestine | 68% | 1565.79 | 656 / 966 | 85% | 20.82 | 449 / 527 |
kidney | 100% | 300.30 | 89 / 89 | 37% | 2.16 | 329 / 901 |
breast | 52% | 62.34 | 239 / 459 | 52% | 5.09 | 582 / 1118 |
prostate | 78% | 61.00 | 191 / 245 | 12% | 0.70 | 58 / 502 |
ovary | 27% | 8.49 | 49 / 180 | 39% | 1.90 | 166 / 430 |
spleen | 62% | 31.88 | 150 / 241 | 0% | 0 | 0 / 0 |
lung | 14% | 6.02 | 79 / 578 | 39% | 4.19 | 450 / 1155 |
esophagus | 9% | 15.55 | 127 / 1445 | 44% | 6.86 | 80 / 183 |
uterus | 21% | 14.48 | 35 / 170 | 27% | 4.14 | 126 / 459 |
bladder | 5% | 5.71 | 1 / 21 | 32% | 9.67 | 160 / 504 |
skin | 13% | 4.78 | 243 / 1809 | 1% | 0.02 | 4 / 472 |
brain | 8% | 2.62 | 216 / 2642 | 1% | 0.04 | 8 / 705 |
adrenal gland | 3% | 1.36 | 8 / 258 | 5% | 0.93 | 12 / 230 |
adipose | 5% | 2.15 | 65 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 3% | 1.20 | 42 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.06 | 1 / 45 |
muscle | 2% | 1.00 | 17 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.03 | 1 / 80 |
peripheral blood | 1% | 0.27 | 5 / 929 | 0% | 0 | 0 / 0 |
heart | 0% | 0.09 | 3 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0009134 | Biological process | nucleoside diphosphate catabolic process |
GO_0009124 | Biological process | nucleoside monophosphate biosynthetic process |
GO_0009133 | Biological process | nucleoside diphosphate biosynthetic process |
GO_0005886 | Cellular component | plasma membrane |
GO_0004382 | Molecular function | GDP phosphatase activity |
GO_0045134 | Molecular function | UDP phosphatase activity |
GO_0004050 | Molecular function | apyrase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
GO_0017111 | Molecular function | ribonucleoside triphosphate phosphatase activity |
Gene name | ENTPD8 |
Protein name | Ectonucleoside triphosphate diphosphohydrolase 8 (EC 3.6.1.5) Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5) |
Synonyms | UNQ2492/PRO5779 |
Description | FUNCTION: Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP. . |
Accessions | ENST00000344119.6 [Q5MY95-2] H7C5J8 ENST00000371506.7 [Q5MY95-1] Q5MY95 ENST00000493135.1 |