Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 6 studies | 26% ± 7% | |
| endothelial cell | 5 studies | 25% ± 8% | |
| plasmacytoid dendritic cell | 4 studies | 20% ± 5% | |
| B cell | 3 studies | 20% ± 4% | |
| plasmablast | 3 studies | 29% ± 10% | |
| microglial cell | 3 studies | 21% ± 3% | |
| GABAergic neuron | 3 studies | 45% ± 5% | |
| glutamatergic neuron | 3 studies | 52% ± 7% | |
| oligodendrocyte precursor cell | 3 studies | 27% ± 8% | |
| interneuron | 3 studies | 37% ± 19% | |
| neuron | 3 studies | 23% ± 5% | |
| astrocyte | 3 studies | 21% ± 3% | |
| oligodendrocyte | 3 studies | 23% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 33% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3874.09 | 1445 / 1445 | 100% | 25.49 | 183 / 183 |
| lung | 100% | 5987.05 | 578 / 578 | 100% | 26.52 | 1154 / 1155 |
| breast | 100% | 4712.32 | 459 / 459 | 100% | 26.68 | 1117 / 1118 |
| prostate | 100% | 5376.11 | 245 / 245 | 100% | 29.98 | 501 / 502 |
| uterus | 100% | 5354.18 | 170 / 170 | 100% | 23.26 | 457 / 459 |
| pancreas | 100% | 3488.31 | 328 / 328 | 99% | 26.31 | 177 / 178 |
| bladder | 100% | 4286.48 | 21 / 21 | 99% | 22.16 | 501 / 504 |
| thymus | 100% | 4790.10 | 653 / 653 | 99% | 19.96 | 601 / 605 |
| skin | 100% | 4248.51 | 1808 / 1809 | 99% | 29.70 | 469 / 472 |
| intestine | 100% | 5261.13 | 966 / 966 | 99% | 21.28 | 522 / 527 |
| stomach | 100% | 3994.38 | 359 / 359 | 99% | 22.31 | 283 / 286 |
| kidney | 100% | 3234.35 | 89 / 89 | 98% | 16.40 | 887 / 901 |
| adrenal gland | 100% | 3250.07 | 258 / 258 | 98% | 34.14 | 225 / 230 |
| brain | 98% | 3026.55 | 2581 / 2642 | 100% | 19.32 | 703 / 705 |
| ovary | 100% | 3798.23 | 180 / 180 | 97% | 11.81 | 416 / 430 |
| liver | 100% | 2123.55 | 226 / 226 | 75% | 7.91 | 304 / 406 |
| adipose | 100% | 4589.89 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 31.70 | 29 / 29 |
| spleen | 100% | 7608.14 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 25.73 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.61 | 1 / 1 |
| blood vessel | 100% | 3596.11 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 2450.08 | 800 / 803 | 0% | 0 | 0 / 0 |
| heart | 99% | 3640.15 | 855 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 3571.84 | 907 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 15.52 | 78 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0046712 | Biological process | GDP catabolic process |
| GO_0046036 | Biological process | CTP metabolic process |
| GO_0034656 | Biological process | nucleobase-containing small molecule catabolic process |
| GO_0006256 | Biological process | UDP catabolic process |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0000421 | Cellular component | autophagosome membrane |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0016020 | Cellular component | membrane |
| GO_0031410 | Cellular component | cytoplasmic vesicle |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0043273 | Molecular function | CTPase activity |
| GO_0004382 | Molecular function | GDP phosphatase activity |
| GO_0036384 | Molecular function | CDP phosphatase activity |
| GO_0045134 | Molecular function | UDP phosphatase activity |
| GO_0017110 | Molecular function | nucleoside diphosphate phosphatase activity |
| GO_0003924 | Molecular function | GTPase activity |
| GO_0017111 | Molecular function | ribonucleoside triphosphate phosphatase activity |
| Gene name | ENTPD4 |
| Protein name | Ectonucleoside triphosphate diphosphohydrolase 4 Ectonucleoside triphosphate diphosphohydrolase 4 (NTPDase 4) (EC 3.6.1.15) (EC 3.6.1.6) (Golgi UDPase) (Lysosomal apyrase-like protein of 70 kDa) (Uridine-diphosphatase) (UDPase) (EC 3.6.1.42) ENTPD4 protein (Ectonucleoside triphosphate diphosphohydrolase 4) |
| Synonyms | KIAA0392 LYSAL1 LALP70 |
| Description | FUNCTION: [Isoform 1]: Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner, with a preference for pyrimidines. Preferentially hydrolyzes UTP and TTP. AMP, ADP, ATP and UMP are not substrates . Preferentially activated by Ca(2+) over Mg(2+) . .; FUNCTION: [Isoform 2]: Has a broad substrate specificity with the ability of cleaving all nucleotide di- and triphosphates with the exception of adenosine di- and triphosphate (ADP and ATP). Preferentially hydrolyzes CTP, UDP, CDP, GTP and GDP. Can use either Ca(2+) or Mg(2+) equally. . |
| Accessions | H0YAN2 ENST00000518471.5 ENST00000417069.6 [Q9Y227-2] ENST00000358689.9 [Q9Y227-1] Q9Y227 ENST00000356206.10 ENST00000519839.1 ENST00000518718.1 Q8NE73 H0YBY8 E5RIB2 |