Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 4 studies | 21% ± 3% | |
epithelial cell | 3 studies | 23% ± 2% | |
GABAergic neuron | 3 studies | 26% ± 12% | |
glutamatergic neuron | 3 studies | 34% ± 11% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
stomach | 96% | 2138.78 | 345 / 359 | 98% | 41.60 | 281 / 286 |
brain | 100% | 3947.26 | 2633 / 2642 | 94% | 37.07 | 663 / 705 |
lung | 100% | 5079.06 | 578 / 578 | 92% | 31.41 | 1061 / 1155 |
intestine | 93% | 3336.79 | 897 / 966 | 98% | 41.03 | 518 / 527 |
thymus | 100% | 2885.85 | 651 / 653 | 90% | 182.86 | 543 / 605 |
pancreas | 94% | 1233.70 | 308 / 328 | 96% | 36.52 | 170 / 178 |
ovary | 98% | 3717.12 | 176 / 180 | 91% | 28.92 | 393 / 430 |
bladder | 86% | 2521.24 | 18 / 21 | 94% | 47.88 | 473 / 504 |
kidney | 100% | 2067.53 | 89 / 89 | 75% | 15.85 | 680 / 901 |
breast | 99% | 2719.40 | 454 / 459 | 68% | 14.06 | 758 / 1118 |
esophagus | 79% | 909.78 | 1135 / 1445 | 82% | 28.22 | 150 / 183 |
liver | 100% | 4734.33 | 226 / 226 | 60% | 12.16 | 245 / 406 |
uterus | 73% | 930.31 | 124 / 170 | 72% | 21.84 | 329 / 459 |
prostate | 96% | 2191.94 | 234 / 245 | 42% | 4.62 | 210 / 502 |
skin | 65% | 695.14 | 1182 / 1809 | 64% | 16.33 | 304 / 472 |
spleen | 100% | 1874.02 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 17.42 | 1 / 1 |
adipose | 99% | 2748.50 | 1190 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 80% | 17.37 | 36 / 45 |
lymph node | 0% | 0 | 0 / 0 | 76% | 12.25 | 22 / 29 |
adrenal gland | 37% | 302.99 | 96 / 258 | 13% | 1.51 | 30 / 230 |
peripheral blood | 35% | 1350.66 | 327 / 929 | 0% | 0 | 0 / 0 |
heart | 34% | 298.98 | 293 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 31% | 345.77 | 413 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 14% | 1.59 | 11 / 80 |
muscle | 3% | 18.97 | 22 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045824 | Biological process | negative regulation of innate immune response |
GO_0016567 | Biological process | protein ubiquitination |
GO_0070936 | Biological process | protein K48-linked ubiquitination |
GO_0007219 | Biological process | Notch signaling pathway |
GO_0032479 | Biological process | regulation of type I interferon production |
GO_0043161 | Biological process | proteasome-mediated ubiquitin-dependent protein catabolic process |
GO_0010498 | Biological process | proteasomal protein catabolic process |
GO_0005813 | Cellular component | centrosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
GO_0008270 | Molecular function | zinc ion binding |
Gene name | DTX4 |
Protein name | E3 ubiquitin-protein ligase DTX4 (EC 2.3.2.27) (Protein deltex-4) (Deltex4) (RING finger protein 155) (RING-type E3 ubiquitin transferase DTX4) |
Synonyms | KIAA0937 RNF155 |
Description | FUNCTION: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4. . |
Accessions | ENST00000227451.4 [Q9Y2E6-1] ENST00000532982.5 [Q9Y2E6-2] Q9Y2E6 |