DOLPP1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DOLPP1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DOLPP1 at tissue level.

III. Associated gene sets

GO_0006489Biological processdolichyl diphosphate biosynthetic process
GO_0006487Biological processprotein N-linked glycosylation
GO_0008610Biological processlipid biosynthetic process
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0047874Molecular functiondolichyldiphosphatase activity

IV. Literature review

[source]
Gene nameDOLPP1
Protein nameDOLPP1 protein
Dolichyldiphosphatase 1 (EC 3.6.1.43) (Dolichyl pyrophosphate phosphatase 1)
Dolichyldiphosphatase 1
SynonymsLSFR2
DescriptionFUNCTION: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity). .

AccessionsH7BXT6
H7C1Z8
Q8IUV4
ENST00000372546.9 [Q86YN1-1]
ENST00000327812.12
Q86YN1
ENST00000412363.1
ENST00000406974.7 [Q86YN1-2]