DNASE2B report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DNASE2B at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DNASE2B at tissue level.

III. Associated gene sets

GO_0006309Biological processapoptotic DNA fragmentation
GO_0005764Cellular componentlysosome
GO_0005576Cellular componentextracellular region
GO_0004531Molecular functiondeoxyribonuclease II activity

IV. Literature review

[source]
Gene nameDNASE2B
Protein nameDeoxyribonuclease-2-beta (EC 3.1.22.1) (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (DNase II beta) (Endonuclease DLAD)
Deoxyribonuclease-2-beta (EC 3.1.22.1) (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (Endonuclease DLAD)
SynonymsDLAD
DescriptionFUNCTION: Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation. .

FUNCTION: Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation. .

FUNCTION: Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation. .

AccessionsQ66K39
Q8WZ79
A0AUY7
ENST00000370662.3 [Q8WZ79-2]
ENST00000370665.4 [Q8WZ79-1]