I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 15 studies | 49% ± 21% | |
| glutamatergic neuron | 3 studies | 17% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 15 studies | 49% ± 21% | |
| glutamatergic neuron | 3 studies | 17% ± 3% |
Insufficient scRNA-seq data for expression of DNAH3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 86% | 898.91 | 498 / 578 | 33% | 1.00 | 384 / 1155 |
| skin | 73% | 126.13 | 1327 / 1809 | 1% | 0.02 | 6 / 472 |
| intestine | 54% | 88.80 | 524 / 966 | 20% | 0.33 | 107 / 527 |
| heart | 70% | 38.44 | 605 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 49% | 15.55 | 161 / 328 | 13% | 0.28 | 23 / 178 |
| esophagus | 34% | 13.77 | 493 / 1445 | 26% | 0.48 | 48 / 183 |
| bladder | 43% | 22.62 | 9 / 21 | 14% | 0.26 | 71 / 504 |
| ovary | 19% | 14.80 | 34 / 180 | 28% | 0.58 | 122 / 430 |
| prostate | 41% | 16.71 | 101 / 245 | 2% | 0.04 | 11 / 502 |
| spleen | 33% | 8.68 | 79 / 241 | 0% | 0 | 0 / 0 |
| brain | 32% | 92.89 | 835 / 2642 | 1% | 0.02 | 5 / 705 |
| uterus | 21% | 168.46 | 36 / 170 | 7% | 0.18 | 33 / 459 |
| stomach | 6% | 1.76 | 21 / 359 | 20% | 0.30 | 58 / 286 |
| kidney | 24% | 7.57 | 21 / 89 | 2% | 0.04 | 20 / 901 |
| muscle | 25% | 16.82 | 198 / 803 | 0% | 0 | 0 / 0 |
| breast | 16% | 6.07 | 75 / 459 | 6% | 0.15 | 65 / 1118 |
| adipose | 10% | 2.80 | 125 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 8% | 3.91 | 76 / 929 | 0% | 0 | 0 / 0 |
| adrenal gland | 8% | 2.15 | 20 / 258 | 0% | 0 | 0 / 230 |
| thymus | 7% | 2.14 | 43 / 653 | 1% | 0.01 | 5 / 605 |
| blood vessel | 6% | 1.55 | 79 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.05 | 1 / 29 |
| liver | 1% | 0.59 | 3 / 226 | 1% | 0.02 | 3 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0060294 | Biological process | cilium movement involved in cell motility |
| GO_0060285 | Biological process | cilium-dependent cell motility |
| GO_0005874 | Cellular component | microtubule |
| GO_0005858 | Cellular component | axonemal dynein complex |
| GO_0097729 | Cellular component | 9+2 motile cilium |
| GO_0030286 | Cellular component | dynein complex |
| GO_0051959 | Molecular function | dynein light intermediate chain binding |
| GO_0008569 | Molecular function | minus-end-directed microtubule motor activity |
| GO_0045505 | Molecular function | dynein intermediate chain binding |
| GO_0003777 | Molecular function | microtubule motor activity |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | DNAH3 |
| Protein name | Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (HsADHC3) (Ciliary dynein heavy chain 3) (Dnahc3-b) Dynein axonemal heavy chain 3 |
| Synonyms | DNAHC3B |
| Description | FUNCTION: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). . |
| Accessions | ENST00000685858.1 ENST00000261383.3 [Q8TD57-1] A0A8V8TLI9 Q8TD57 ENST00000698260.1 A0A8I5KSE2 |
