I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 5 studies | 25% ± 7% | |
| epithelial cell | 4 studies | 22% ± 7% | |
| GABAergic neuron | 3 studies | 26% ± 5% | |
| glutamatergic neuron | 3 studies | 36% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 5 studies | 25% ± 7% | |
| epithelial cell | 4 studies | 22% ± 7% | |
| GABAergic neuron | 3 studies | 26% ± 5% | |
| glutamatergic neuron | 3 studies | 36% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1591.07 | 1445 / 1445 | 100% | 33.68 | 183 / 183 |
| ovary | 100% | 1597.78 | 180 / 180 | 100% | 25.32 | 430 / 430 |
| stomach | 100% | 1261.29 | 359 / 359 | 100% | 30.09 | 286 / 286 |
| intestine | 100% | 1783.89 | 966 / 966 | 100% | 31.20 | 526 / 527 |
| skin | 100% | 1749.13 | 1809 / 1809 | 100% | 28.82 | 471 / 472 |
| lung | 100% | 1217.11 | 576 / 578 | 100% | 23.44 | 1154 / 1155 |
| breast | 100% | 1442.15 | 459 / 459 | 100% | 23.00 | 1113 / 1118 |
| bladder | 100% | 1716.43 | 21 / 21 | 99% | 23.34 | 501 / 504 |
| thymus | 100% | 1639.03 | 653 / 653 | 99% | 14.11 | 600 / 605 |
| uterus | 100% | 2001.80 | 170 / 170 | 99% | 20.32 | 455 / 459 |
| brain | 99% | 910.49 | 2620 / 2642 | 100% | 18.91 | 704 / 705 |
| prostate | 100% | 1379.35 | 245 / 245 | 99% | 16.17 | 496 / 502 |
| pancreas | 100% | 1013.01 | 327 / 328 | 99% | 15.80 | 176 / 178 |
| kidney | 100% | 1039.92 | 89 / 89 | 98% | 17.54 | 882 / 901 |
| adrenal gland | 100% | 1370.52 | 258 / 258 | 97% | 12.73 | 223 / 230 |
| liver | 100% | 799.40 | 225 / 226 | 94% | 11.08 | 382 / 406 |
| adipose | 100% | 1362.28 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1524.88 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 15.70 | 29 / 29 |
| muscle | 100% | 1567.04 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1206.68 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 16.88 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 9.84 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 99% | 23.91 | 79 / 80 |
| heart | 97% | 997.45 | 832 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 49% | 646.58 | 455 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0003341 | Biological process | cilium movement |
| GO_0036158 | Biological process | outer dynein arm assembly |
| GO_0036159 | Biological process | inner dynein arm assembly |
| GO_0120293 | Cellular component | dynein axonemal particle |
| GO_0031514 | Cellular component | motile cilium |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0045505 | Molecular function | dynein intermediate chain binding |
| Gene name | DNAAF5 |
| Protein name | Dynein axonemal assembly factor 5 Dynein axonemal assembly factor 5 (HEAT repeat-containing protein 2) |
| Synonyms | HEATR2 |
| Description | FUNCTION: Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility. . |
| Accessions | ENST00000437419.5 ENST00000297440.11 [Q86Y56-1] E9PGY2 ENST00000403952.3 H7C3B1 Q86Y56 H0Y650 ENST00000440747.5 |
