DEFB136 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DEFB136 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DEFB136 at tissue level.

III. Associated gene sets

GO_0050829Biological processdefense response to Gram-negative bacterium
GO_0140367Biological processantibacterial innate immune response
GO_0031640Biological processkilling of cells of another organism
GO_0061760Biological processantifungal innate immune response
GO_0050830Biological processdefense response to Gram-positive bacterium
GO_0005576Cellular componentextracellular region
GO_0001530Molecular functionlipopolysaccharide binding

IV. Literature review

[source]
Gene nameDEFB136
Protein nameDefensin beta 136 (Beta-defensin 136) (DEFB137)
Synonyms
DescriptionFUNCTION: Host defense peptide that exhibits antibacterial and antifungal activity . Exhibits antimicrobial activity against E.coli, S.aureus and C.albicans (in vitro) . Has high lipopolysaccharide (LPS)-binding affinity, and may thereby be involved in immunoregulation through LPS neutralization . .

AccessionsENST00000646795.1
ENST00000382209.2
Q30KP8